Email this article Simultaneous laparoscopic liver resection: a single-center experience
- Authors: Akhaladze G.G.1, Grebenkin E.N.1, Chkhikvadze V.D.1, Stanojević U.S.1, Goncharov S.V.1, Ragimov V.A.1, Kolesnikov R.V.1, Abramov A.A.1
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Affiliations:
- Russian Research Center of Roentgenoradiology
- Issue: Vol 46, No 6 (2018)
- Pages: 592-597
- Section: ARTICLES
- URL: https://almclinmed.ru/jour/article/view/898
- DOI: https://doi.org/10.18786/20720505-2018-46-6-592-597
- ID: 898
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Abstract
Background: About 15 to 25% of colorectal cancer patients have synchronous liver metastasis at diagnosis. In the recent years, the strategy of simultaneous removal of colorectal cancer and liver metastases has been preferred. Development of minimally invasive technologies in abdominal and hepatopancreatobiliary surgery allows for active advance to fully laparoscopic approach to these types of interventions.
Aim: Comparative analysis of simultaneous and isolated laparoscopic liver resections performed in the Department of Surgery, Russian Research Center of Roentgenoradiology (Moscow).
Materials and methods: We have analyzed intra- and postoperative results of 29 laparoscopic procedures for metastatic liver disease. Group 1 included 14 patients who had undergone simultaneous laparoscopic primary tumor resection and laparoscopic liver resection for metastatic disease. Group 2 included 15 patients who had undergone isolated laparoscopic liver resection for metastatic lesions.
Results: Mean (± SD) blood loss in the simultaneous and isolated procedures groups was 469 ± 176 and 408 ± 124 mL, respectively (p = 0.2), whereas the duration of surgeries was 296 ± 107 and 204 ± 82 min, respectively (p = 0.01). Conversion rate in the isolated resection group was higher (26% vs. 14%). This difference is to be explained by the learning curve in laparoscopic liver surgery. All liver resections in both groups were carried out in R0 mode. No deaths and significant complications were seen in any of the groups.
Conclusion: The study demonstrated feasibility and safety of simultaneous, fully laparoscopic liver resections, including those for difficult localization of primary tumors and metastatic lesions.
About the authors
G. G. Akhaladze
Russian Research Center of Roentgenoradiology
Email: fake@neicon.ru
Guram G. Akhaladze – MD, PhD, Professor, Chief Research Fellow, Research Department of Surgery and Surgical Technologies in Oncology.
86 Profsoyuznaya ul., Moscow, 117997
РоссияE. N. Grebenkin
Russian Research Center of Roentgenoradiology
Author for correspondence.
Email: genbytu@mail.ru
Egor N. Grebenkin – MD, PhD, Research Fellow, Research Department of Surgery and Surgical Technologies in Oncology.
86 Profsoyuznaya ul., Moscow, 117997, tel.: +7 (985) 295 01 88
РоссияV. D. Chkhikvadze
Russian Research Center of Roentgenoradiology
Email: fake@neicon.ru
Vladimir D. Chkhikvadze – MD, PhD, Professor, Head of the Research Department of Surgery and Surgical Technologies in Oncology.
86 Profsoyuznaya ul., Moscow, 117997
РоссияU. S. Stanojević
Russian Research Center of Roentgenoradiology
Email: fake@neicon.ru
Uglješa S. Stanojević – MD, PhD, Senior Research Fellow, Research Department of Surgery and Surgical Technologies in Oncology.
86 Profsoyuznaya ul., Moscow, 117997
РоссияS. V. Goncharov
Russian Research Center of Roentgenoradiology
Email: fake@neicon.ru
Sergey V. Goncharov – MD, PhD, Head of the Department of Abdominal Surgery.
86 Profsoyuznaya ul., Moscow, 117997
РоссияV. A. Ragimov
Russian Research Center of Roentgenoradiology
Email: fake@neicon.ru
Vadim A. Ragimov – Junior Research Fellow, Research Department of Surgery and Surgical Technologies in Oncology.
86 Profsoyuznaya ul., Moscow, 117997
РоссияR. V. Kolesnikov
Russian Research Center of Roentgenoradiology
Email: fake@neicon.ru
Roman V. Kolesnikov – MD, PhD, Surgeon Oncologist, Department of Abdominal Surgery.
86 Profsoyuznaya ul., Moscow, 117997
РоссияA. A. Abramov
Russian Research Center of Roentgenoradiology
Email: fake@neicon.ru
Aleksey A. Abramov – MD, PhD, Surgeon Oncologist, Department of Abdominal Surgery.
86 Profsoyuznaya ul., Moscow, 117997
РоссияReferences
- Piros L, Máthé Z. Laparoscopy in liver surgery. Magy Onkol. 2018;62(1): 37–44.
- Xie SM, Xiong JJ, Liu XT, Chen HY, Iglesia-García D, Altaf K, Bharucha S, Huang W, Nunes QM, Szatmary P, Liu XB. Laparoscopic versus open liver resection for colorectal liver metastases: a comprehensive systematic review and meta-analysis. Sci Rep. 2017;7(1): 1012. doi: 10.1038/s41598-017-00978-z.
- Aghayan DL, Pelanis E, Avdem Fretland Å, Kazaryan AM, Sahakyan MA, Røsok BI, Barkhatov L, Bjørnbeth BA, Jakob Elle O, Edwin B. Laparoscopic parenchyma-sparing liver resection for colorectal metastases. Radiol Oncol. 2017;52(1): 36–41. doi: 10.1515/raon-20170046.
- Buell JF, Cherqui D, Geller DA, O'Rourke N, Iannitti D, Dagher I, Koffron AJ, Thomas M, Gayet B, Han HS, Wakabayashi G, Belli G, Kaneko H, Ker CG, Scatton O, Laurent A, Abdalla EK, Chaudhury P, Dutson E, Gamblin C, D'Angelica M, Nagorney D, Testa G, Labow D, Manas D, Poon RT, Nelson H, Martin R, Clary B, Pinson WC, Martinie J, Vauthey JN, Goldstein R, Roayaie S, Barlet D, Espat J, Abecassis M, Rees M, Fong Y, McMasters KM, Broelsch C, Busuttil R, Belghiti J, Strasberg S, Chari RS; World Consensus Conference on Laparoscopic Surgery. The international position on laparoscopic liver surgery: The Louisville Statement, 2008. Ann Surg. 2009;250(5): 825–30. doi: 10.1097/SLA.0b013e3181b3b2d8.
- Wakabayashi G, Cherqui D, Geller DA, Buell JF, Kaneko H, Han HS, Asbun H, O'Rourke N, Tanabe M, Koffron AJ, Tsung A, Soubrane O, Machado MA, Gayet B, Troisi RI, Pessaux P, Van Dam RM, Scatton O, Abu Hilal M, Belli G, Kwon CH, Edwin B, Choi GH, Aldrighetti LA, Cai X, Cleary S, Chen KH, Schön MR, Sugioka A, Tang CN, Herman P, Pekolj J, Chen XP, Dagher I, Jarnagin W, Yamamoto M, Strong R, Jagannath P, Lo CM, Clavien PA, Kokudo N, Barkun J, Strasberg SM. Recommendations for laparoscopic liver resection: a report from the second international consensus conference held in Morioka. Ann Surg. 2015;261(4): 619–29. doi: 10.1097/SLA.0000000000001184.
- Abu Hilal M, Aldrighetti L, Dagher I, Edwin B, Troisi RI, Alikhanov R, Aroori S, Belli G, Besselink M, Briceno J, Gayet B, D'Hondt M, Lesurtel M, Menon K, Lodge P, Rotellar F, Santoyo J, Scatton O, Soubrane O, Sutcliffe R, Van Dam R, White S, Halls MC, Cipriani F, Van der Poel M, Ciria R, Barkhatov L, Gomez-Luque Y, Ocana-Garcia S, Cook A, Buell J, Clavien PA, Dervenis C, Fusai G, Geller D, Lang H, Primrose J, Taylor M, Van Gulik T, Wakabayashi G, Asbun H, Cherqui D. The Southampton Consensus Guidelines for laparoscopic liver surgery: from indication to implementation. Ann Surg. 2018;268(1): 11–8. doi: 10.1097/SLA.0000000000002524.
- Siriwardena AK, Mason JM, Mullamitha S, Hancock HC, Jegatheeswaran S. Management of colorectal cancer presenting with synchronous liver metastases. Nat Rev Clin Oncol. 2014;11(8): 446–59. doi: 10.1038/nrclinonc.2014.90.
- Ivanecz A, Krebs B, Stozer A, Jagric T, Plahuta I, Potrc S. Simultaneous pure laparoscopic resection of primary colorectal cancer and synchronous liver metastases: a single institution experience with propensity score matching analysis. Radiol Oncol. 2017;52(1): 42–53. doi: 10.1515/raon-2017-0047.
- Wei M, He Y, Wang J, Chen N, Zhou Z, Wang Z. Laparoscopic versus open hepatectomy with or without synchronous colectomy for colorectal liver metastasis: a meta-analysis. PLoS One. 2014;9(1):e87461. doi: 10.1371/journal.pone.0087461.
- Ikeda T, Mano Y, Morita K, Hashimoto N, Kayashima H, Masuda A, Ikegami T, Yoshizumi T, Shirabe K, Maehara Y. Pure laparoscopic hepatectomy in semiprone position for right hepatic major resection. J Hepatobiliary Pancreat Sci. 2013;20(2): 145–50. doi: 10.1007/s00534-012-0558-y.
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