The first experience with the fully-covered self-expandable nitinol stents in the management of anastomotic biliary strictures after orthotopic liver transplantation

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Abstract

Background: Biliary anastomosis strictures after orthotopic liver transplantation (OLT) develop in 5–12% of patients. This complication significantly impairs the patients’ quality of life and can lead to graft loss.

Aim: To analyze the first experience in the use of coated self-expanding nitinol stents in patients with biliary anastomosis strictures after OLT.

Materials and methods: From December 2018 to January 2019, there were 5 patients with anastomotic strictures after OLT in the Department of Organ and/or Tissue Transplantation of the S.P. Botkin Municipal Clinical Hospital. All patients underwent endoscopic stenting of strictures with a self-expanding nitinol-coated stent. In all patients, the stent was removed at 3 months after its placement.

Results: No complications and deaths were recorded in this patient group. The median duration of the follow-up after stent removal was 14.15 ± 2.35 (3–17) months, with no cases of restenosis identified.

Conclusion: The use of coated nitinol stents in the management of patients with anastomotic strictures after liver transplantation is effective and safe. The possibility of their use in routine clinical practice requires confirmation in further studies.

About the authors

A. V. Shabunin

Russian Medical Academy of Continuous Professional Education; S.P. Botkin Municipal Clinical Hospital

Email: fake@neicon.ru
ORCID iD: 0000-0002-0522-0681

Alexey V. Shabunin – MD, PhD, Professor, Corr. Member of Russ. Acad. Sci., Head of Chair of Surgery; Chief Physician

2/1–1 Barrikadnaya ul., Moscow, 125993; 5 2-y Botkinskiy proezd, Moscow, 125284

Russian Federation

I. Yu. Korzheva

Russian Medical Academy of Continuous Professional Education; S.P. Botkin Municipal Clinical Hospital

Email: fake@neicon.ru
ORCID iD: 0000-0002-5984-5660

Irina Yu. Korzheva – MD, PhD, Professor, Chair of Endoscopy; Head of Department of Endoscopy

2/1–1 Barrikadnaya ul., Moscow, 125993; 5 2-y Botkinskiy proezd, Moscow, 125284

Russian Federation

G. M. Chechenin

Russian Medical Academy of Continuous Professional Education; S.P. Botkin Municipal Clinical Hospital

Email: fake@neicon.ru
ORCID iD: 0000-0002-4883-2389

Grigory M. Chechenin – MD, PhD, Associate Professor, Chair of Surgery; Surgeon

2/1–1 Barrikadnaya ul., Moscow, 125993; 5 2-y Botkinskiy proezd, Moscow, 125284

Russian Federation

S. S. Lebedev

Russian Medical Academy of Continuous Professional Education; S.P. Botkin Municipal Clinical Hospital

Email: fake@neicon.ru
ORCID iD: 0000-0001-5366-1281

Sergey S. Lebedev – MD, PhD, Associate Professor, Head of Teaching Department, Chair of Surgery; Head of In-Patient Facility of Ambulatory Cancer Care

2/1–1 Barrikadnaya ul., Moscow, 125993; 5 2-y Botkinskiy proezd, Moscow, 125284

Russian Federation

P. A. Drozdov

S.P. Botkin Municipal Clinical Hospital

Author for correspondence.
Email: dc.drozdov@gmail.com
ORCID iD: 0000-0001-8016-1610

Pavel A. Drozdov – MD, PhD, Head of Department of Organ and/or Tissue Transplantation

15–8 Brusilova ul., Moscow, 117148

Tel.: +7 (962) 985 04 41

Russian Federation

O. S. Zhuravel

Russian Medical Academy of Continuous Professional Education; S.P. Botkin Municipal Clinical Hospital

Email: fake@neicon.ru
ORCID iD: 0000-0002-8225-0024

Olesya S. Zhuravel – Senior Assistant, Chair of Surgery; Surgeon

2/1–1 Barrikadnaya ul., Moscow, 125993; 5 2-y Botkinskiy proezd, Moscow, 125284

Russian Federation

S. A. Astapovich

I.M. Sechenov First Moscow State Medical University

Email: fake@neicon.ru
ORCID iD: 0000-0001-7774-1892

Sergey A. Astapovich – Student, Faculty of General Medicine, International School “Medicine in the Future”

8/2 Trubetskaya ul., Moscow, 119991

Russian Federation

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Copyright (c) 2020 Shabunin A.V., Korzheva I.Y., Chechenin G.M., Lebedev S.S., Drozdov P.A., Zhuravel O.S., Astapovich S.A.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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