QUALITY OF LIFE IN PATIENTS WITH CHRONIC PANCREATITIS IN THE MOSCOW REGION

Cover Page


Cite item

Full Text

Abstract

Rationale: Chronic pancreatitis is characterized by progression with gradual insufficiency of pancreas and can be associated with complications. Various clinical signs and symptoms of the disease may affect patient's quality of life.
Aim: To assess quality of life in various groups of patients with chronic pancreatitis, living in the Moscow Region, who have uncomplicated and complicated course of the disease, depending on their compliance level, compared to that in patients regularly seen by doctors of other specialities.
Materials and methods: One hundred patients with chronic pancreatitis living in the Moscow Region completed the Medical Outcomes Study – Short Form (MOS SF-36) questionnaire.
Results: In chronic pancreatitis patients, there was a clear decrease in quality of life parameters on all subscales. It was found that the presence of any complications did not contribute to deterioration of quality of life, with no significant difference in quality of life parameters in any subscale (р > 0.05). Quality of life was better in the patients who were fully adherent to their treatment (n = 28). In non-compliant patients (n = 72), there was a significant decrease (р < 0,05) of the following quality of life parameters: physical role functioning (29 points), emotional role functioning (45 points), as well as general health (32 points), pain intensity (44 points) and social functioning (51 point). Patients who were regularly seen by a gastroenterologist, had better quality of life (р < 0.05), compared to those seen by an internist, on the following subscales: physical role functioning (56 and 29 points, respectively), pain (60 and 45), general health (46 and 31), vitality (48 and 32), social functioning (69 and 52), emotional functioning (75 and 46). In patients who had not been regularly seen by any doctor, there was a statistically significant decrease in quality of life (р < 0.05) on the same subscales (0, 24, 17, 22, 35, 17 points, respectively).
Conclusion: To improve quality of life in patients with chronic pancreatitis, it is necessary to increase the level of doctor's knowledge in pancreatology, to improve patient adherence to treatment, to ensure regular visit to doctors, as well as to establish the continuity of treatment from an in-patient to an out-patient unit.

About the authors

S. V. Belyakova

Orekhovo-Zuevo Central City Hospital, Orekhovo-Zuevo, Moskovskaya oblast'

Author for correspondence.
Email: sve79@yandex.ru
Belyakova Svetlana Valentinovna – Gastroenterologist Россия

E. A. Belousova

Moscow Regional Research and Clinical Institute

Email: sve79@yandex.ru
Belousova Elena Aleksandrovna – MD, PhD, Professor, Head of Department of Gastroenterology and Hepatology Россия

References

  1. Маев ИВ, Казюлин АН, Кучерявый ЮА. Хронический панкреатит. М.: Медицина; 2005. 504 с.
  2. Ивашкин ВТ, Маев ИВ, Охлобыстин АВ, Кучерявый ЮА, Трухманов АС, Шептулин АА, Шифрин ОС, Лапина ТЛ, Осипенко МФ, Симаненков ВИ, Хлынов ИБ, Алексеенко СА, Алексеева ОП, Чикунова МВ. Рекомендации Российской гастроэнтерологической ассоциации по диагностике и лечению хронического панкреатита. Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2014;24(4):70–97.
  3. Lévy P, Domínguez-Muñoz E, Imrie C, Löhr M, Maisonneuve P. Epidemiology of chronic pancreatitis: burden of the disease and consequences. United European Gastroenterol J. 2014;2(5):345–54. doi: 10.1177/2050640614548208.
  4. Mitchell RM, Byrne MF, Baillie J. Pancreatitis. Lancet. 2003;361(9367):1447–55.
  5. Баранов АА, Климанская ЕВ, Римарчук ГВ, ред. Детская гастроэнтерология: избранные главы. М.: Научный центр здоровья детей РАМН; 2002. 592 с.
  6. Lowenfels AB, Maisonneuve P, Cavallini G, Ammann RW, Lankisch PG, Andersen JR, Dimagno EP, Andrén-Sandberg A, Domellöf L. Pancreatitis and the risk of pancreatic cancer. International Pancreatitis Study Group. N Engl J Med. 1993;328(20):1433–7.
  7. Malka D, Hammel P, Sauvanet A, Rufat P, O’Toole D, Bardet P, Belghiti J, Bernades P, Ruszniewski P, Lévy P. Risk factors for diabetes mellitus in chronic pancreatitis. Gastroenterology. 2000;119(5):1324–32.
  8. Ammann RW. Natural history of chronic pancreatitis. Dig Surg. 1994;11:267–74.
  9. Thuluvath PJ, Imperio D, Nair S, Cameron JL. Chronic pancreatitis. Long-term pain relief with or without surgery, cancer risk, and mortality. J Clin Gastroenterol. 2003;36(2):159–65.
  10. Калинин АВ, Логинов АФ, Хазанов АИ, ред. Гастроэнтерология и гепатология: диагностика и лечение. Руководство для врачей. М.: МЕДпресс-информ; 2013. 848 c.
  11. Waljee AK, Dimagno MJ, Wu BU, Schoenfeld PS, Conwell DL. Systematic review: pancreatic enzyme treatment of malabsorption associated with chronic pancreatitis. Aliment Pharmacol Ther. 2009;29(3):235–46. doi: 10.1111/j.1365- 2036.2008.03885.x.
  12. Talamini G, Bassi C, Butturini G, Falconi M, Casetti L, Gumbs AA, Carrara S, Fantin A, Pederzoli P. Outcome and quality of life in chronic pancreatitis. JOP. 2001;2(4):117–23.
  13. Armbrecht U. Chronic pancreatitis: weight loss and poor physical performance – experience from a specialized rehabilitation centre. Rehabilitation (Stuttg). 2001;40(6):332–6.
  14. Lévy P, Barthet M, Mollard BR, Amouretti M, Marion-Audibert AM, Dyard F. Estimation of the prevalence and incidence of chronic pancreatitis and its complications. Gastroenterol Clin Biol. 2006;30(6–7):838–44.
  15. World Health Organization. “WHO Definition of Health”, citing the Preamble to the Constitution of the World Health Organization as adopted by the International Health Conference, New York, 19–22 June, 1946; signed on 22 July 1946 by the representatives of 61 States (Official Records of the World Health Organization, no. 2, p. 100). Available from: http://www.who. int/about/definition/en/print.html
  16. What quality of life? The WHOQOL Group. World Health Organization Quality of Life Assessment. World Health Forum. 1996;17(4):354–6.
  17. Шишкова ЮА, Мотовилин ОГ, Суркова ЕВ, Майоров АЮ. Качество жизни при сахарном диабете: определение понятия, современные подходы к оценке, инструменты для исследования. Сахарный диабет. 2011;(3):70–5.
  18. Snoek FJ. Quality of life: a closer look at measuring patients' well-being. Diabetes Spectrum. 2000;13:24–8.
  19. Вассерман ЛИ, Трифонова ЕА. Дискуссионные вопросы концептуализации и методологии исследования качества жизни в медицине. Сибирский психологический журнал. 2007;(26):112–9.
  20. Ware JE, Kosinski M, Gandek B. SF-36 Health Survey: Manual and Interpretation Guide. Lincoln, RI: Quality Metric Incorporated; 2000.
  21. Савченко ТН, Головина ГМ. Субъективное качество жизни: подходы, методы оценки, прикладные исследования. М.: Издательство Института психологии РАН; 2006. 168 с.
  22. Новик АА, Ионова ТИ. Руководство по исследованию качества жизни в медицине. М.: ОЛМА Медиа Групп; 2007. 320 с.
  23. Черногорова МВ, Белоусова ЕА, Гуров АН. Сравнительная характеристика качества лечения и качества жизни гастроэнтерологических больных в условиях наблюдения гастроэнтерологом и терапевтом. Экспериментальная и клиническая гастроэнтерология. 2004;(3):89–96.
  24. Кашкина ЕИ, Листишенкова ЮВ. Взаимосвязь клинического течения хронического билиарнозависимого панкреатита с показателями качества жизни и приверженности пациентов к поддерживающей терапии. Саратовский научно-медицинский журнал. 2009;5(2):203–7.
  25. Белякова СВ, Белоусова ЕА. Приверженность к лечению больных хроническим панкреатитом в Московской области. Альманах клинической медицины. 2014;33:64–70.
  26. Белякова СВ, Белоусова ЕА. Оценка качества амбулаторного лечения хронического панкреатита в Московской области. Медицинский совет. 2014;(13):46–8.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2015 Belyakova S.V., Belousova E.A.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies