Email this article ACITRETIN IN THE TREATMENT OF GRZYBOWSKI TYPE ERUPTIVE KERATOACANTHOMA
- Authors: Kuntsevich Z.S.1,2, Molochkova Y.V.1,2, Bobrov M.A.1,2, Khlebnikova A.N.3,4, Dibirova S.D.3,4
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Affiliations:
- Moscow Regional Research and Clinical Institute (MONIKI)
- 61/2 Shchepkina ul., Moscow, 129110, Russian Federation
- I.M. Sechenov First Moscow State Medical University
- 8/2 Trubetskaya ul., Moscow, 119991, Russian Federation
- Issue: Vol 44, No 1 (2016)
- Pages: 96-102
- Section: DERMATO-ONCOLOGY
- URL: https://almclinmed.ru/jour/article/view/313
- DOI: https://doi.org/10.18786/2072-0505-2016-44-1-96-102
- ID: 313
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Abstract
The article describes a case of successful treatment of multiple eruptive keratoacanthoma of Grzybowski in a 82-year old woman with concomitant advanced heart disease and chronic gastritis. The tumor was diagnosed in 1 of 256 patients with keratoacanthoma who attend our clinic, i.e. in 0,39% keratoacanthoma cases in general and in 0,96% among atypical keratoacanthomas. HLA-A2 gene characteristic for atypical keratoacanthomas was found in this patient. Acitretin was administered for 3 months at a daily dose of 20 mg. The treatment resulted in a full regression of the elements with residual areas of scarry atrophy and/or depigmentation. Flattening of the elements was obvious after 2 weeks. The patient tolerated the treatment well.
About the authors
Zh. S. Kuntsevich
Moscow Regional Research and Clinical Institute(MONIKI); 61/2 Shchepkina ul., Moscow, 129110, Russian Federation
Author for correspondence.
Email: j_s_k@mail.ru
MD, PhD, Associate Professor, Chair of Dermatovenereology and Dermato-
oncology, Postgraduate Training Faculty
Yu. V. Molochkova
Moscow Regional Research and Clinical Institute(MONIKI); 61/2 Shchepkina ul., Moscow, 129110, Russian Federation
Email: j_s_k@mail.ru
MD, PhD, Senior Research Fellow, Dermatovenereology and Dermato-oncology Department
РоссияM. A. Bobrov
Moscow Regional Research and Clinical Institute(MONIKI); 61/2 Shchepkina ul., Moscow, 129110, Russian Federation
Email: j_s_k@mail.ru
MD, Research Fellow, Depart- ment of Pathological Anatomy
РоссияA. N. Khlebnikova
I.M. Sechenov First Moscow State Medical University; 8/2 Trubetskaya ul., Moscow, 119991, Russian Federation
Email: j_s_k@mail.ru
MD, PhD, Professor, Chair of Skin and Venereal Diseases, Institute for Professional Education
РоссияS. D. Dibirova
I.M. Sechenov First Moscow State Medical University; 8/2 Trubetskaya ul., Moscow, 119991, Russian Federation
Email: j_s_k@mail.ru
MD, PhD Student, Chair of Skin and Venereal Diseases, Institute for Professional
Education
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