THE ANGIOTROPHONEUROSES. ERYTHROMELALGIA IN A 11-YEAR OLD CHILD

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  • Authors: Tamrazova O.B.1,2,3, Molochkov A.V.4,5, Koren'kova O.V.6,3, Novikov K.A.7,8
  • Affiliations:
    1. Peoples' Friendship University of Russia
    2. 6 Mikluho-Maklaya ul., Moscow, 117198, Russian Federation Bashlyaeva Municipal Pediatric Clinical Hospital, Moscow
    3. 28 Geroev Panfilovtsev ul., Moscow, 125373, Russian Federation
    4. Moscow Regional Research and Clinical Institute (MONIKI)
    5. 61/2 Shchepkina ul., Moscow, 129110, Russian Federation
    6. Bashlyaeva Municipal Pediatric Clinical Hospital, Moscow
    7. Clinic of Active Longevity “The Beauty Institute In Arbat”
    8. 8 Malyy Nikolopeskovskiy pereulok, Moscow, 119002, Russian Federation
  • Issue: Vol 44, No 1 (2016)
  • Pages: 52-57
  • Section: DERMATOLOGY
  • URL: https://almclinmed.ru/jour/article/view/307
  • DOI: https://doi.org/10.18786/2072-0505-2016-44-1-52-57
  • ID: 307


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Abstract

The article deals with angiotrophoneuroses, a large group of heterogenous disorders with an underlying dysfunction of vascular innervation. A  current classification of vegetovascular neuroses, their triggers and clinical manifestations are described. The main attention is paid to a  rare disease, erythromelalgia that is сharacterized by acute attacks of dilatation of small vessel of the extremities with associated severe pain, skin hyperemia and edema. We present a  clinical case of primary erythromelalgia in a 11-year old child. The complexity of diagnostics and treatment of the case were related to a combination of classical manifestation of the disease with advanced mental problems resulting in autoagressive behavior.

About the authors

O. B. Tamrazova

Peoples' Friendship University of Russia; 6 Mikluho-Maklaya ul., Moscow, 117198, Russian Federation
Bashlyaeva Municipal Pediatric Clinical Hospital, Moscow; 28 Geroev Panfilovtsev ul., Moscow, 125373, Russian Federation

Author for correspondence.
Email: anait_tamrazova@mail.ru

Tamrazova Ol'ga B. – MD, PhD, Professor, Chair of Dermatovenereology, Postgraduate Medical Training Faculty1; Consultant Physician2   

Россия

A. V. Molochkov

Moscow Regional Research and Clinical Institute (MONIKI); 61/2 Shchepkina ul., Moscow, 129110, Russian Federation

Email: anait_tamrazova@mail.ru

MD, PhD, Professor, Deputy Director on Science and International Communications

Россия

O. V. Koren'kova

Bashlyaeva Municipal Pediatric Clinical Hospital, Moscow; 28 Geroev Panfilovtsev ul., Moscow, 125373, Russian Federation

Email: anait_tamrazova@mail.ru
MD, Surgeon Россия

K. A. Novikov

Clinic of Active Longevity “The Beauty Institute In Arbat”; 8 Malyy Nikolopeskovskiy pereulok, Moscow, 119002, Russian Federation

Email: anait_tamrazova@mail.ru
MD, Dermatovenereologist Россия

References

  1. Smith LA, Allen EV. Erythermalgia (erythromelalgia) of extremities: a syndrome character-ized by redness, heat, and pain. Am Heart J. 1938;16175–88.
  2. Waxman SG, Dib-Hajj SD. Erythromelalgia: a hereditary pain syndrome enters the molecular era. Ann Neurol. 2005;57(6):785–8. doi: 10.1002/ana.20511.
  3. Yang Y, Wang Y, Li S, Xu Z, Li H, Ma L, Fan J, Bu D, Liu B, Fan Z, Wu G, Jin J, Ding B, Zhu X, Shen Y. Mutations in SCN9A, encoding a sodium channel alpha subunit, in patients with primary erythermalgia. J Med Genet. 2004;41(3):171–4. doi: 10.1136/jmg.2003.012153.
  4. Sandroni P, Davis MD, Harper CM, Rogers RS 3rd, Harper CM Jr, Rogers RS 3rd, O'Fallon WM, Rooke TW, Low PA. Neurophysiologic and vascular studies in erythromelalgia: a retrospective analysis. J Clin Neuromuscul Dis. 1999;1(2):57–63.
  5. Mork C, Asker CL, Salerud EG, Kvernebo K. Microvascular arteriovenous shunting is a probable pathogenetic mechanism in erythromelalgia. J Invest Dermatol. 2000;114(4): 643–6.
  6. Littleford RC, Khan F, Belch JJ. Impaired skin vasomotor reflexes in patients with erythromelalgia. Clin Sci (Lond). 1999;96(5):507–12. doi: 10.1042/cs0960507.
  7. Mørk C, Kalgaard OM, Kvernebo K. Impaired neurogenic control of skin perfusion in erythromelalgia. J Invest Dermatol. 2002;118(4):699–703.
  8. Davis MD, O'Fallon WM, Rogers RS 3rd, Rooke TW. Natural history of erythromelalgia: presentation and outcome in 168 patients. Arch Dermatol. 2000;136(3):330–6. doi: 10.1001/archderm.136.3.330.
  9. Davis MD, Sandroni P, Rooke TW, Low PA. Erythromelalgia: vasculopathy, neuropathy, or both? A prospective study of vascular and neurophysiologic studies in erythromelalgia. Arch Dermatol. 2003;139(10):1337–43. doi: 10.1001/archderm.139.10.1337.
  10. Belch JJF. Temperature-associated vascular disorders: Raynaud's phenomenon and erythromelalgia. In: Tooke JE, Lowe GD, editors. A textbook of vascular medicine. London: Arnold; 1996. p. 329–52.
  11. Herskovitz S, Loh F, Berger AR, Kucherov M. Erythromelalgia: association with hereditary sensory neuropathy and response to amitriptyline. Neurology. 1993;43(3 Pt 1):621–2.

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Copyright (c) 2016 Tamrazova O.B., Molochkov A.V., Koren'kova O.V., Novikov K.A.

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