RELAPSE PREVENTION AND IMPROVEMENT OF RESULTS OF COMPLEX ARRHYTHMIAS’ SURGICAL CORRECTION IN CARDIAC PATIENTS

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Abstract

Aim: To examine results of surgical intervention in cardiac surgery patients with atrial fibrillation after a loading pre-operative dose of amiodarone.

Material and methods: The study included 49 cardiac patients with atrial fibrillation who underwent a surgery during a 14 months’ period in 2013–2014. Group 1 (n = 23) received preoperative amiodarone saturation at a dose 0.6–1.0 g daily with a maintenance dose 0.4 g daily in early postoperative period and at a dose 0.2 g daily up to 6 months after surgery. Group 2 (control, n = 26) was on a postoperative maintenance dose of amiodarone 0.6–1.0 g daily.

Results: Stable sinus rhythm after left atrial Maze IV procedure was established in 44/49 of patients (90%). Atrial fibrillation relapsed in 1 patient from group 1 and in 4 patients from group 2. All 5 patients with recurrence of persistent atrial fibrillation had a long-term persistent arrhythmic history of more than 3 years, and echocardiography revealed left atrial dilatation of more than 6 cm.

Conclusion: The use of saturating doses of amiodarone before surgery improves outcomes of left atrial Maze IV procedure (up to 95%), compared to those in the control group where amiodarone was used postoperatively (up to 85%).

About the authors

N. A. Trofimov

Republican Cardiology Dispensary

Author for correspondence.
Email: nikolai.trofimov@mail.ru

Cardiovascular Surgeon

Россия

A. P. Medvedev

Nizhny Novgorod State Medical Academy

Email: mail@skkbnn.ru

MD, PhD, Professor, Head of Chair of Hospital Surgery named after B.A. Korolyov

Россия

V. E. Babokin

Moscow Regional Research and Clinical Institute (MONIKI)

Email: babokin@bk.ru

PhD, Head of Department of Cardiac Surgery

Россия

O. I. Demarin

Nizhny Novgorod State Medical Academy

Email: fake@neicon.ru
Cardiovascular Surgeon Россия

N. Kh. Zhamlikhanov

Municipal Pediatric Hospital No. 4

Email: fake@neicon.ru

MD, PhD, Professor, Chief Physician

Россия

A. G. Dragunov

Republican Cardiology Dispensary

Email: fake@neicon.ru

PhD, Head of Department of Cardiac Surgery No. 2

Россия

M. V. Gartfelder

Republican Cardiology Dispensary

Email: fake@neicon.ru

Cardiovascular Surgeon

Россия

O. V. Nikolaeva

Republican Cardiology Dispensary

Email: fake@neicon.ru
Cardiologist Россия

M. V. Dragunova

Republican Cardiology Dispensary

Email: fake@neicon.ru
Cardiologist Россия

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Copyright (c) 2015 Trofimov N.A., Medvedev A.P., Babokin V.E., Demarin O.I., Zhamlikhanov N.K., Dragunov A.G., Gartfelder M.V., Nikolaeva O.V., Dragunova M.V.

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