EGALLOHIT GEL IN PATIENTS WITH LASER-INDUCED THERMOTHERAPY OF SUPERFICIAL AND MICRONODULAR BASALIOMA

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Abstract

Background: In basalioma, facial skin is frequent- E-mail: mmacosmetology@mail.ru ly affected. Thus, good cosmetological effect of treatment and anti-tumor efficacy are both important. Optimal approach includes prevention of pathological scarring. In many cases, preventive measures ensure normal scarring even after invasive methods of treatment. Aim: To assess efficacy and safety of Egallohit gel and its effects on scarring in patients with laser-induced thermotherapy (LITT) of basalioma. Materials and methods: 42 patients with superficial and micronodular basaliomas were included. LITT is a new highly effective and less invasive method providing satisfactory cosmetic results. Comprehensive treatment involved LITT (1 or 2 cycles) with subsequent application of Egallohit gel (up to 30 days after the intervention). Results: After the first LITT, clinical cure of basalioma was demonstrated in 41  (97.6%) patients. In one patient with superficial basalioma clinical cure was achieved after the second cycle of LITT. After epithelization of the tumor site, excellent and good clinical result was observed in 15 (35.7%) and 22 (52.5%) patients, respectively (satisfactory results were found only in 5 cases (11,8%), p<0,05). According to the Likert scale scores, 40  patients (95.2%) were very satisfied and 2  patients (4.8%) were satisfied with the treatment. Conclusion: Adding Egallohit after LITT in patients with basaliomas resulted in reduction of connective tissue growth in the lesions, promoted scar tissue resolution and surface smoothening (especially during scar formation), inhibited hyperemia and pigmentation and improved elasticity and displaceability of surrounding tissues.

About the authors

E. I. Tret’yakova

Moscow Regional Research and Clinical Institute (MONIKI); 61/2 Shchepkina ul., Moscow, 129110, Russian Federation

Email: fake@neicon.ru
MD, PhD, Research Associate, Dermatovenereology and Dermato-Oncology Department Russian Federation

T. E. Sukhova

Moscow Regional Research and Clinical Institute (MONIKI); 61/2 Shchepkina ul., Moscow, 129110, Russian Federation

Email: fake@neicon.ru
MD, PhD, Senior Research Associate, Dermatovenereology and Dermato-Oncology Department Russian Federation

O. V. Matveeva

I.M. Sechenov First Moscow State Medical University; 8/2 Trubetskaya ul., Moscow, 119991,
Russian Federation

Author for correspondence.
Email: mmacosmetology@mail.ru
MD, PhD, Associate Professor, Department of Skin and Venereal Diseases, Institute for Professional Education Russian Federation

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Copyright (c) 2014 Tret’yakova E.I., Sukhova T.E., Matveeva O.V.

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