Email this article Preoperative mechanical bowel preparation combined with oral antibacterials in the prevention of complications of surgery for rectal and rectosigmoid junction cancer
- Authors: Ivanov Y.V.1,2, Smirnov A.V.1, Vinokurov A.V.1, Zlobin A.I.1, Stankevich V.R.1, Danilina E.S.1
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Affiliations:
- Federal Scientific and Clinical Center for Specialized Types of Medical Care and Medical Technologies
- A.I. Evdokimov Moscow State University of Medicine and Dentistry
- Issue: Vol 49, No 7 (2021)
- Pages: 477-484
- Section: ARTICLES
- URL: https://almclinmed.ru/jour/article/view/1618
- DOI: https://doi.org/10.18786/2072-0505-2021-49-062
- ID: 1618
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Abstract
Aim: To evaluate the efficacy of mechanical bowel preparation (MBP) combined with oral antibacterials for the prevention of postoperative complications when preparing a patient for anterior rectal resection.
Materials and methods: We analyzed shortterm results in 77 patients who had undergone anterior rectal resection for rectal and rectosigmoid junction cancer. Forty five (45) patients were prepared for surgery only with MBP. In 32 patients, in addition to MBP, oral antibacterial agents ciprofloxacin and metronidazole were used preoperatively.
Results: The overall rate of postoperative complications was 6.25% (2/32 patients) in the group of combined preparation for surgery and 15.5% (7/45) in the group using only MBP. Surgical wound infection occurred in 1 patient in the combined preparation group and in 4 patients in the MBP only group. There was no anastomotic leak in the combined preparation group, whereas in the MBP only group, anastomotic leak occurred in 2 patients.
Conclusion: Combined use of oral antibacterials and MBP before anterior rectal resection makes it possible to achieve an extremely low rate of the colorectal anastomosis leak. Further studies into the efficacy of this preparation regimen are needed, along with their discussion in the professional communities.
About the authors
Yu. V. Ivanov
Federal Scientific and Clinical Center for Specialized Types of Medical Care and Medical Technologies;A.I. Evdokimov Moscow State University of Medicine and Dentistry
Email: ivanovkb83@yandex.ru
ORCID iD: 0000-0001-6209-4194
Yuri V. Ivanov – MD, PhD, Professor, Head of Department of Surgery Federal Scientific and Clinical Center for Specialized Types of Medical Care and Medical Technologies; Chief Research Fellow, Laboratory of Minimally Invasive Surgery A.I. Evdokimov Moscow State University of Medicine and Dentistry
28 Orekhovyy bul'var, Moscow, 115682,
20–1 Delegatskaya ul., Moscow, 127473
РоссияA. V. Smirnov
Federal Scientific and Clinical Center for Specialized Types of Medical Care and Medical Technologies
Author for correspondence.
Email: alvsmirnov@mail.ru
ORCID iD: 0000-0003-3897-8306
Alexander V. Smirnov – MD, PhD, Surgeon, Department of Surgery
28 Orekhovyy bul'var, Moscow, 115682
Россия
A. V. Vinokurov
Federal Scientific and Clinical Center for Specialized Types of Medical Care and Medical Technologies
Email: vinokuroff.sasha2015@yandex.ru
ORCID iD: 0000-0001-8026-1216
Aleksandr V. Vinokurov – Resident, Chair of Surgery, Academy of Postgraduate Education
28 Orekhovyy bul'var, Moscow, 115682
РоссияA. I. Zlobin
Federal Scientific and Clinical Center for Specialized Types of Medical Care and Medical Technologies
Email: fake@neicon.ru
Alexander I. Zlobin – MD, PhD, Surgeon, Department of Surgery
28 Orekhovyy bul'var, Moscow, 115682
РоссияV. R. Stankevich
Federal Scientific and Clinical Center for Specialized Types of Medical Care and Medical Technologies
Email: v-stankevich@yandex.ru
ORCID iD: 0000-0002-8620-8755
Vladimir R. Stankevich – Surgeon, Department of Surgery
28 Orekhovyy bul'var, Moscow, 115682
РоссияE. S. Danilina
Federal Scientific and Clinical Center for Specialized Types of Medical Care and Medical Technologies
Email: danilina.katja@bk.ru
ORCID iD: 0000-0002-2466-3795
Ekaterina S. Danilina – Surgeon, Department of Surgery; Senior Laboratory Assistant, Chair of Surgery, Academy of Postgraduate Education
28 Orekhovyy bul'var, Moscow, 115682
РоссияReferences
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