Email this article The method of inhalation analgesia with sevoflurane during spontaneous delivery
- Authors: Upriamova E.Y.1, Shifman E.M.2, Krasnopol'skiy V.I.1, Ovezov A.M.2, Novikova S.V.1, Bocharova I.I.1, El'chaninova A.G.1
-
Affiliations:
- Moscow Regional Scientific Research Institute for Obstetrics and Gynecology
- Moscow Regional Research and Clinical Institute (MONIKI)
- Issue: Vol 47, No 3 (2019)
- Pages: 196-203
- Section: ARTICLES
- URL: https://almclinmed.ru/jour/article/view/1074
- DOI: https://doi.org/10.18786/2072-0505-2019-47-034
- ID: 1074
Cite item
Full Text
Abstract
Background: The search for methods for protection against delivery and labor pains has led to resumption of studies of non-invasive, safe and effective labor analgesia and inhalational anesthesia that could be used both separately and in combination with other methods. Recent research has demonstrated the highest efficacy of sevoflurane for analgesia of spontaneous delivery.
Aim: To develop an optimized and effective method of inhalational analgesia with sevoflurane for spontaneous delivery.
Materials and methods: We have performed a prospective study of the efficacy of inhalational sevoflurane for analgesia of spontaneous delivery. Thirty three obstetric patients were given sevoflurane-oxygen mixture according to a specially designed technique. The pain intensity was assessed with a visual analogous scale (VAS), sedation level, with Ramsay scale and Richmond Agitation-Sedation Scale (RASS).
Results: The mean duration of inhalational anesthesia was 92.1±28 minutes [60–180']. There were no refusals and no switching to another type of analgesia. After induction of analgesia with Funding sevoflurane, there was a significant decrease of pain intensity by VAS by 34.9% from the baseline level (p = 0.00003); the pain was assessed as “moderate”. This trend was maintained throughout the whole exposure period.
Conclusion: The results obtained confirm the possibility to use the proposed method of inhalational analgesia with sevoflurane to ensure effective analgesia in obstetric patients during delivery and labor.
About the authors
E. Yu. Upriamova
Moscow Regional Scientific Research Institute for Obstetrics and Gynecology
Author for correspondence.
Email: kvyalkova@gmail.com
ORCID iD: 0000-0002-7057-2149
Ekaterina Yu. Upriamova – MD, PhD, Head of Department of Anesthesiology and Intensive Care.
22a Pokrovka ul., Moscow, 101000, Tel.: +7 (906) 710 38 35
Russian FederationE. M. Shifman
Moscow Regional Research and Clinical Institute (MONIKI)
Email: fake@neicon.ru
ORCID iD: 0000-0002-6113-8498
Efim M. Shifman – MD, PhD, Professor, Chair of Anesthesiology and Reanimatology, Postgraduate Training Faculty.
61/2 Shchepkina ul., Moscow, 129110
Russian FederationV. I. Krasnopol'skiy
Moscow Regional Scientific Research Institute for Obstetrics and Gynecology
Email: fake@neicon.ru
Vladislav I. Krasnopol'skiy – MD, PhD, Professor, Member of Russian Academy of Sciences, President.
22a Pokrovka ul., Moscow, 101000
Russian FederationA. M. Ovezov
Moscow Regional Research and Clinical Institute (MONIKI)
Email: fake@neicon.ru
ORCID iD: 0000-0001-7629-6280
Aleksey M. Ovezov – MD, PhD, Associate Professor, Head of Department of Anesthesiology, Head of Chair of Anesthesiology and Reanimatology, Postgraduate Training Faculty.
61/2 Shchepkina ul., Moscow, 129110
Russian FederationS. V. Novikova
Moscow Regional Scientific Research Institute for Obstetrics and Gynecology
Email: fake@neicon.ru
Svetlana V. Novikova – MD, PhD, Professor, Head of Observational Obstetric Department.
22a Pokrovka ul., Moscow, 101000
Russian FederationI. I. Bocharova
Moscow Regional Scientific Research Institute for Obstetrics and Gynecology
Email: fake@neicon.ru
Irina I. Bocharova – MD, PhD, Leading Research Fellow, Department of Neonatology.
22a Pokrovka ul., Moscow, 101000
Russian FederationA. G. El'chaninova
Moscow Regional Scientific Research Institute for Obstetrics and Gynecology
Email: fake@neicon.ru
Anastasiya G. El'chaninova – MD, Postgraduate Student, Observational Obstetric Department.
22a Pokrovka ul., Moscow, 101000
Russian FederationReferences
- Alleemudder DI, Kuponiyi Y, Kuponiyi C, McGlennan A, Fountain S, Kasivisvanathan R. Analgesia for labour: an evidence-based insight for the obstetrician. The Obstetrician & Gynaecologist. 2015;17(3):147–55. doi: 10.1111/tog.12196.
- Упрямова ЕЮ, Шифман ЕМ, Овезов АМ, Новикова СВ, Ельчанинова АГ, Чаплыгина ОВ. Влияние методов обезболивания самопроизвольных родов на организм матери и плода. Альманах клинической медицины. 2018;46(2):137–45. doi: 10.18786/2072-05052018-46-2-137-145.
- Anwari JS, Khalil L, Terkawi AS. Efficacy of the methoxyflurane as bridging analgesia during epidural placement in laboring parturient. Saudi J Anaesth. 2015;9(4):370–5. doi: 10.4103/1658-354X.159457.
- Klomp T, van Poppel M, Jones L, Lazet J, Di Nisio M, Lagro-Janssen AL. Inhaled analgesia for pain management in labour. Cochrane Database Syst Rev. 2012;(9):CD009351. doi: 10.1002/14651858.CD009351.pub2.
- Yeo ST, Holdcroft A, Yentis SM, Stewart A, Bassett P. Analgesia with sevoflurane during labour: ii. Sevoflurane compared with Entonox for labour analgesia. Br J Anaesth. 2007;98(1): 110–5. doi: 10.1093/bja/ael327.
- Ng KWS, Chan Y, Shariffuddin II, Yim CCW, Md Latar IL, Eltringham R, Moy Y. Abstract PR210: Sevonox Study A Comparison of 0.8% Sevoflurane & Entonox for Labour Analgesia. Anesth Analg. 2016;123(3 Suppl):271–2. doi: 10.1213/01.ane.0000492608.13239.1e.
- Toscano A, Pancaro C, Giovannoni S, Minelli G, Baldi C, Guerrieri G, Crowhurst JA, Peduto VA. Sevoflurane analgesia in obstetrics: a pilot study. Int J Obstet Anesth. 2003;12(2):79–82. doi: 10.1016/S0959-289X(02)00195-4.
- Балихин ИЛ, Кабачков ЕН, Куркин ЕН, Мартыненко ВМ, Троицкий ВН, Домашнев ИА, Упрямова ЕЮ, Шифман ЕМ, Овезов АМ. Перспективы использования фотокаталитической технологии очистки воздуха для обеспечения безопасности применения севофлурана при обезболивании родов в акушерском стационаре. Химия высоких энергий. 2018;52(4):343–6. doi: 10.1134/S0023119318040034.
- Пальчик АБ, Шабалов НП. Гипоксически-ишемическая энцефалопатия новорожденных. 2-е изд., испр. и доп. М.: МЕДпресс-информ; 2006. 256 с.
- Гржибовский АМ, Иванов СВ, Горбатова МА. Сравнение количественных данных трех и более парных выборок с использованием программного обеспечения Statistica и SPSS: параметрические и непараметрические критерии. Наука и здравоохранение. 2016;(5):5–29.
- Tallent R, Corcoran J, Sebastian J. Evaluation of a novel waste anaesthetic gas scavenger device for use during recovery from anaesthesia. Anaesthesia. 2018;73(1):59–64. doi: 10.1111/anae.14100.
Supplementary files
