The clinical decision support system for sepsis as an important part of the medical and economic component of a hospital
- Authors: Gorban V.I.1, Bakhtin M.Y.1, Shchegolev A.V.2, Lobanova Y.V.1
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Affiliations:
- Nikiforov Russian Center of Emergency and Radiation Medicine
- Military Medical Academy
- Issue: Vol 47, No 3 (2019)
- Pages: 204-211
- Section: ARTICLES
- URL: https://almclinmed.ru/jour/article/view/995
- DOI: https://doi.org/10.18786/2072-0505-2019-47-010
- ID: 995
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Full Text
Abstract
Aim: To evaluate an impact of a clinical decision support system (CDSS) in the clinical practice of a hospital on the quality and costs of treatment of patients with severe sepsis and septic shock.
Materials and methods: We performed a retrospective analysis of the database in the medical information system qMS (SP.ARM, Russia, St. Petersburg) from 2015 to 2017 on 37,997 patients. In the first study period from January 2015 to June 2016, we analyzed the results of the conventional treatment regimen. From May to June 2016, the CDSS module was implemented into the qMS and the personnel was trained correspondingly. The data collected during the second study period mirrored the results of sepsis treatment with the use of CDSS. We assessed the average number of in-hospital days, duration of stay in the intensive care unit, number of septic shock cases, mortality, and treatment costs.
Results: The diagnosis of sepsis was confirmed in 67 patients: in 1.4‰ (27/18,792) before the CDSS was implemented versus 2.1‰ (40/19,205) after the CDSS implementation (p < 0.01). It was found that the use of CDSS integrated into the hospital medical information system reduced the number of cases of septic shock development (p < 0.05). Lethality decreased by 10%. The sepsis-associated mortality showed a non-significant trend to decrease by 10% (p < 0.1). The implementation of the CDSS incorporated into the qMS helped to reduce the number of septic shock cases from 26% (7/27) to 7.5% (3/40) (p < 0.05). There was also a trend towards reduced duration of stay in intensive care unit, as well as towards decreased costs of sepsis treatment by 13% and efferent (extra-corporeal) treatments by 29%; however, the differences were not significant.
Conclusion: The CDSS implementation for electronic monitoring of the patient's condition and changes in his/hers parameters allowed for an earlier diagnosis of sepsis. We identified some prerequisites for more rational utilization of medical resources, mainly due to early, targeted treatment of patients with severe sepsis and septic shock; however, additional studies are necessary.
About the authors
V. I. Gorban
Nikiforov Russian Center of Emergency and Radiation Medicine
Author for correspondence.
Email: ms.gorban@inbox.ru
Vera I. Gorban - MD, PhD, Head of the Department of Anesthesiology and Reanimation (neurologic disorders and injures).
54 Optikov ul., Saint Petersburg, 197345, Tel.: +7 (921) 795 64 99
РоссияM. Yu. Bakhtin
Nikiforov Russian Center of Emergency and Radiation Medicine
Email: fake@neicon.ru
Mikhail Yu. Bakhtin - MD, PhD, Chief Medical Information Officer.
4/2 Akademika Lebedeva ul., Saint Petersburg, 194044
РоссияA. V. Shchegolev
Military Medical Academy
Email: fake@neicon.ru
Aleksei V. Shchegolev - MD, PhD, Head of the Department of Anesthesiology and Resuscitation.
6 Akademika Lebedeva ul., Saint Petersburg, 194044
РоссияYu. V. Lobanova
Nikiforov Russian Center of Emergency and Radiation Medicine
Email: fake@neicon.ru
Yulia V. Lobanova - MD, PhD, Assistant Director of Patient Care.
4/2 Akademika Lebedeva ul., Saint Petersburg, 194044
РоссияReferences
- Лудупова ЕЮ. Врачебные ошибки. Литературный обзор. Вестник Росздравнадзора. 2016;(2): 6–15.
- Гусев АВ, Зарубина ТВ. Поддержка принятия врачебных решений в медицинских информационных системах медицинской организации. Врач и информационные технологии. 2017;(2): 60–72.
- Liu V, Escobar GJ, Greene JD, Soule J, Whippy A, Angus DC, Iwashyna TJ. Hospital deaths in patients with sepsis from 2 independent cohorts. JAMA. 2014;312(1): 90–2. doi: 10.1001/jama.2014.5804.
- Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med. 2001;29(7): 1303–10.
- Савельев ВС, Гельфанд БР, ред. Сепсис: классификация, клинико-диагностическая концепция и лечение. 3-е изд. М.: МИА; 2013. 360 с.
- Manaktala S, Claypool SR. Evaluating the impact of a computerized surveillance algorithm and decision support system on sepsis mortality. J Am Med Inform Assoc. 2017;24(1): 88–95. doi: 10.1093/jamia/ocw056.
- Edbrooke DL, Hibbert CL, Kingsley JM, Smith S, Bright NM, Quinn JM. The patient-related costs of care for sepsis patients in a United Kingdom adult general intensive care unit. Crit Care Med. 1999;27(9): 1760–7.
- Edbrooke D, Hibbert C, Ridley S, Long T, Dickie H. The development of a method for comparative costing of individual intensive care units. The Intensive Care Working Group on Costing. Anaesthesia. 1999;54(2): 110–20. doi: 10.1046/j.1365-2044.1999.00650.x.
- Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb SA, Beale RJ, Vincent JL, Moreno R; Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med. 2013;41(2): 580–637. doi: 10.1097/CCM.0b013e31827e83af.
- Клинические рекомендации по диагностике и лечению тяжелого сепсиса и септического шока в лечебно-профилактических организациях Санкт-Петербурга [Интернет]. Доступно на: https://www.spbsepsis.ru/wp-content/uploads/Protocols_24_11_2016.pdf.
- Генеральные тарифные соглашения на 2015, 2016, 2017 годы Территориального фонда обязательного медицинского страхования Санкт-Петербурга [Интернет]. Доступно на:https://spboms.ru/page/docs.