AN EXAMPLE OF A MULTIFACETED APPROACH TO DIAGNOSTICS AND TREATMENT OF UROGENITAL REACTIVE ARTHRITIS (REITER’S DISEASE)

Cover Page


Cite item

Full Text

Abstract

Urogenital reactive arthritis (Reiter's disease) is a  vital interdisciplinary problem due to multiple symptoms of the disease, their appearance at different times, inadequate clinical alertness of specialist, as well as to the necessity of significant efforts both from the part of the doctor and the patient during the process of multifaceted diagnostics. Based on a  clinical case, we demonstrate a classical clinical manifestation of urogenital reactive arthritis that was initially administered incongruent symptomatic treatment resulting only to temporary attenuation of one of the symptoms. We illustrate a comprehensive approach to management, assessment and treatment of the patient based on the causal factor, pathophysiologic characteristics of the disease and immunologic criteria, with the use of immunomorphological skin investigation, photopheresis and lymphotropic therapy.

About the authors

A. V. Molochkov

Moscow Regional Research and Clinical Institute
(MONIKI); 61/2 Shchepkina ul., Moscow, 129110, Russian Federation

Email: marina.s.petrova@gmail.com
MD, PhD, Professor, Deputy Director on Science and International Communications Россия

M. S. Petrova

Moscow Regional Research and Clinical Institute
(MONIKI); 61/2 Shchepkina ul., Moscow, 129110, Russian Federation

Author for correspondence.
Email: marina.s.petrova@gmail.com
MD, Research Fellow, Dermato- venereology and Dermato-oncology Department Россия

References

  1. Rihl M, Klos A, Köhler L, Kuipers JG. Infection and musculoskeletal conditions: Reactive arthritis. Best Pract Res Clin Rheumatol. 2006;20(6):1119–37. doi: 10.1016/j. berh.2006.08.008.
  2. Насонов ЕЛ, Насонова ВА, ред. Ревматология. Национальное руководство. М.: ГЭОТАР-Медиа; 2010. 720 с.
  3. Хандсфилд Х. Заболевания, передающиеся половым путем. Цветной атлас-справочник. Пер. с англ. М.: Бином; 2006. 296 с.
  4. Butler MJ, Russell AS, Percy JS, Lentle BC. A follow-up study of 48 patients with Reiter's syndrome. Am J Med. 1979;67(5):808–10.
  5. Savolainen E, Kaipiainen-Seppänen O, Kröger L, Luosujärvi R. Total incidence and distribution of inflammatory joint diseases in a defined population: results from the Kuopio 2000 arthritis survey. J Rheumatol. 2003;30(11):2460–8.
  6. Kvien TK, Gaston JS, Bardin T, Butrimiene I, Dijkmans BA, Leirisalo-Repo M, Solakov P, Altwegg M, Mowinckel P, Plan PA, Vischer T; EULAR. Three month treatment of reactive arthritis with azithromycin: a EULAR double blind, placebo controlled study. Ann Rheum Dis. 2004;63(9):1113–9. doi: 10.1136/ ard.2003.010710.
  7. Kobayashi S, Ando S. Reactive arthritis or Reiter's syndrome and B51-associated seronegative spondyloarthropathy. Intern Med. 2000;39(2):89. doi: http://doi.org/10.2169/internalmedicine.39.89.
  8. Hamdulay SS, Glynne SJ, Keat A. When is arthritis reactive? Postgrad Med J. 2006;82(969):446– 53. doi: 10.1136/pgmj.2005.044057.
  9. Ковалев ЮН, Молочков ВА, Петрова МС. Бо- лезнь Рейтера. М.: ГЭОТАР-Медиа; 2006. 224 с.
  10. Meador R, Hsia E, Kitumnuaypong T, Schumacher HR. TNF involvement and anti-TNF therapy of reactive and unclassified arthritis. Clin Exp Rheumatol. 2002;20(6 Suppl 28): S130–4.
  11. Kellner H, Wen J, Wang J, Raybourne RB, Williams KM, Yu DT. Serum antibodies from patients with ankylosing spondylitis and Reiter's syndrome are reactive with HLA-B27 cells transfected with the Mycobacterium tuberculosis hsp60 gene. Infect Immun. 1994;62(2):484–91.
  12. Караулов АВ, Афанасьева СС, Алешкина ВА, Лапина БА, ред. Хламидийная инфекция. Новые аспекты патогенеза, иммунологии, верификации и лечения инфекции у человека и приматов. М.: Первый МГМУ им. И.М. Сеченова; 2012. 256 c.
  13. Молочков ВА, Кильдюшевский АВ, Молочков АВ. Фотоферез в дерматовенерологии. М.: БИНОМ; 2014. 152 с.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2016 Molochkov A.V., Petrova M.S.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies