SURGICAL TREATMENT OF COMPLEX ARRHYTHMIAS IN PATIENTS WITH NON-ISCHEMIC MITRAL INSUFFICIENCY

Cover Page


Cite item

Full Text

Abstract

Aim: To analyze and improve efficacy of surgical treatment of patients with non-ischemic mitral insufficiency and atrial fibrillation.

Materials and methods: The study included 64 patients with degenerative mitral insufficiency complicated by atrial fibrillation who had surgical interventions from 2011 to 2014. Surgical treatment consisted of surgical correction of mitral regurgitation: mitral valve reconstruction (group 1, n = 133) and mechanical prosthesis (group 2, n = 31), as well as left atrium Maze IV procedure in “box lesion” modification with the use of AtriCure bipolar destructor in both groups.

Results: No postoperative deaths were registered. After surgery, all patients showed a decrease in all cardiac cavities’ sizes and of pulmonary hypertension, an improvement in left ventricular systolic function assessed by transthoracic echocardiography. During follow-up of up to 14 months’ duration, sinus rhythm was maintained in 56 (86%) of patients, whereas 9 patients had recurrent atrial fibrillation resistant to medications and electrical cardioversion. Patients, who had undergone valve preserving correction of mitral insufficiency and left atrium Maze IV procedure, had the best results as to contractility of left ventricle (7.86%), reduction of cardiac cavities’ size (end-diastolic dimension – 11.05%, end-systolic dimension – 15.15%, right atrium – 15.19%), especially that of left atrium (19.03%), reduction of pulmonary hypertension (27.75%) and significant improvement in quality of life (7 points) assessed by Minnesota Living with Heart Failure Questionnaire.

Conclusion: Plastic correction of mitral insufficiency with atrial fibrillation combined with Maze IV procedure gives the highest improvement of left ventricular contractility and diminishing of cavities compared to mitral valve replacement with mechanical prosthesis in combination with Maze IV procedure.

About the authors

N. A. Trofimov

Republican Cardiology Dispensary

Author for correspondence.
Email: nikolai.trofimov@mail.ru

Cardiovascular Surgeon

Россия

A. P. Medvedev

Nizhny Novgorod State Medical Academy

Email: mail@skkbnn.ru

MD, PhD, Professor, Head of Chair of Hospital Surgery named after B.A. Korolyov

Россия

V. E. Babokin

Moscow Regional Research and Clinical Institute (MONIKI)

Email: babokin@bk.ru

PhD, Head of Department of Cardiac Surgery

Россия

O. I. Demarin

Nizhny Novgorod State Medical Academy

Email: fake@neicon.ru
Cardiovascular Surgeon Россия

N. Kh. Zhamlikhanov

Municipal Pediatric Hospital No. 4

Email: fake@neicon.ru

MD, PhD, Professor, Chief Physician

Россия

A. G. Dragunov

Republican Cardiology Dispensary

Email: fake@neicon.ru

PhD, Head of Department of Cardiac Surgery No. 2

Россия

M. V. Gartfelder

Republican Cardiology Dispensary

Email: fake@neicon.ru

Cardiovascular Surgeon

Россия

O. V. Nikolaeva

Republican Cardiology Dispensary

Email: fake@neicon.ru
Cardiologist Россия

M. V. Dragunova

Republican Cardiology Dispensary

Email: fake@neicon.ru
Cardiologist Россия

A. Yu. Eldyrev

Republican Cardiology Dispensary

Email: fake@neicon.ru

PhD, Specialist in Anesthesiology/Resuscitation

Россия

T. N. Vladimirova

Republican Cardiology Dispensary

Email: fake@neicon.ru
Cardiologist Россия

References

  1. Дземешкевич СЛ, Стивенсон ЛУ, АлексиМесхишвили ВВ. Болезни аортального клапана. Функция, диагностика, лечение. М.: ГЭОТАР-Медиа, 2004. 325 с. Dzemeshkevich SL, Stivenson LU, Aleksi-Meskhishvili VV. Bolezni aortal'nogo klapana.Funktsiya, diagnostika, lechenie [Aortic valve disease. Functioning, diagnosis, treatment]. Moscow: GEOTAR-Media; 2004. 325 p. (in Russian).
  2. Bonow RO, Carabello B, de Leon AC Jr, Edmunds LH Jr, Fedderly BJ, Freed MD, Gaasch WH, McKay CR, Nishimura RA, O'Gara PT, O'Rourke RA, Rahimtoola SH, Ritchie JL, Cheitlin MD, Eagle KA, Gardner TJ, Garson A Jr, Gibbons RJ, Russell RO, Ryan TJ, Smith SC Jr. Guidelines for the management of patients with valvular heart disease: executive summary. A report of the American College of Cardiology / American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients with Valvular Heart Disease). Circulation. 1998;98(18):1949–84.
  3. Bryhn M, Persson S. The prevalence of mitral valve prolapse in healthy men and women in Sweden. An echocardiographic study. Acta Med Scand. 1984;215(2):157–60.
  4. Devereux RB, Hawkins I, Kramer-Fox R, Lutas EM, Hammond IW, Spitzer MC, Hochreiter C, Roberts RB, Belkin RN, Kligfield P. Complications of mitral valve prolapse. Disproportionate occurrence in men and older patients. Am J Med. 1986;81(5):751–8.
  5. Freed LA, Levy D, Levine RA, Larson MG, Evans JC, Fuller DL, Lehman B, Benjamin EJ. Prevalence and clinical outcome of mitral-valve prolapse. N Engl J Med. 1999;341(1):1–7.
  6. Nishimura RA, McGoon MD. Perspectives on mitral-valve prolapse. N Engl J Med. 1999;341(1):48–50.
  7. Procacci PM, Savran SV, Schreiter SL, Bryson AL. Prevalence of clinical mitral-valve prolapse in 1169 young women. N Engl J Med. 1976;294(20):1086–8.
  8. Wilcken DE, Hickey AJ. Lifetime risk for patients with mitral valve prolapse of developing severe valve regurgitation requiring surgery. Circulation. 1988;78(1):10–4.
  9. Warth DC, King ME, Cohen JM, Tesoriero VL, Marcus E, Weyman AE. Prevalence of mitral valve prolapse in normal children. J Am Coll Cardiol. 1985;5(5):1173–7.
  10. Reid CL, Anton-Culver H, Yunis C, Gardin JM. Prevalence and clinical correlates of isolated mitral, isolated aortic regurgitation, and both in adults aged 21 to 35 years (from the CARDIA study). Am J Cardiol. 2007;99(6):830–4.
  11. Singh JP, Evans JC, Levy D, Larson MG, Freed LA, Fuller DL, Lehman B, Benjamin EJ. Prevalence and clinical determinants of mitral, tricuspid, and aortic regurgitation (the Framingham Heart Study). Am J Cardiol. 1999;83(6):897–902.
  12. Jones EC, Devereux RB, Roman MJ, Liu JE, Fishman D, Lee ET, Welty TK, Fabsitz RR, Howard BV. Prevalence and correlates of mitral regurgitation in a population-based sample (the Strong Heart Study). Am J Cardiol. 2001;87(3):298–304.
  13. Бокерия ЛА, Гудкова РГ. Сердечно-сосудистая хирургия. М.: НЦССХ им. А.Н. Бакулева РАМН; 2008. 181 с. Bokeriya LA, Gudkova RG. Serdechno-sosudistaya khirurgiya [Cardiovascular surgery]. Moscow: NTsSSKh im. A.N. Bakuleva RAMN [Bakulev Scientific Center of Cardiovascular Surgery]; 2008. 181 p. (in Russian).
  14. Караськов AM, Горбатых ЛВ, Семенов ИИ, Семенова ЕИ. Пути оптимизации кардио-хирургической службы Сибирского федерального округа (2002–2007 гг.). Патология кровообращения и кардиохирургия. 2009;(1):3–5. Karas'kov AM, Gorbatykh LV, Semenov II, Semenova EI. Puti optimizatsii kardiokhirurgicheskoy sluzhby Sibirskogo federal'nogo okruga (2002–2007 gg.) [Optimization of cardiovascular surgery care in the Sibirian Federal District (2002–2007)]. Patologiya krovoobrashcheniya i kardiokhirurgiya [Circulation Pathology and Cardiosurgery]. 2009;(1):3–5 (in Russian).
  15. Национальные рекомендации по ведению, диагностике и лечению клапанных пороков сердца. М.: НЦССХ им. А.Н. Бакулева; 2009. 356 с. Natsional'nye rekomendatsii po vedeniyu, diagnostike i lecheniyu klapannykh porokov serdtsa [Guidelines on management, diagnosis and treatment of valvular heart disease]. Мoscow: NTsSSKh im. A.N. Bakuleva RAMN [Bakulev Scientific Center of Cardiovascular Surgery]; 2009. 356 p. (in Russian).
  16. Adams DH, Rosenhek R, Falk V. Degenerative mitral valve regurgitation: best practice revolution. Eur Heart J. 2010;31(16):1958–66.
  17. Chen MC, Chang JP, Chen YL. Surgical treatment of atrial fibrillation with concomitant mitral valve disease: an Asian review. Chang Gung Med J. 2008;31(6):538–45.
  18. Jahangiri M, Weir G, Mandal K, Savelieva I, Camm J. Current strategies in the management of atrial fibrillation. Ann Thorac Surg. 2006;82(1):357–64.
  19. Джорджикия РК, Харитонов ГИ. Современные аспекты диагностики и хирургического лечения приобретенных пороков сердца. Практическая медицина. 2003;(2):25–6. Dzhordzhikiya RK, Kharitonov GI. Sovremennye aspekty diagnostiki i khirurgicheskogo lecheniya priobretennykh porokov serdtsa [Advances in diagnosis and surgical treatment of acquired valve disease]. Prakticheskaya meditsina [Practical Medicine]. 2003;(2):25–6 (in Russian).
  20. Kalil RA, Maratia CB, D'Avila A, Ludwig FB. Predictive factors for persistence of atrial fibrillation after mitral valve operation. Ann
  21. Thorac Surg. 1999;67(3):614–7.
  22. Kim JB, Ju MH, Yun SC, Jung SH, Chung CH, Choo SJ, Lee TY, Song H, Lee JW. Mitral valve replacement with or without a concomitant Maze procedure in patients with atrial fibrillation. Heart. 2010;96(14):1126–31.
  23. Raine D, Dark J, Bourke JP. Effect of mitral valve repair/replacement surgery on atrial arrhythmia behavior. J Heart Valve Dis.
  24. ;13(4):615–21.
  25. Grigioni F, Avierinos JF, Ling LH, Scott CG, Bailey KR, Tajik AJ, Frye RL, Enriquez-Sarano M. Atrial fibrillation complicating the course of degenerative mitral regurgitation: determinants and long-term outcome. J Am Coll Cardiol. 2002;40(1):84–92.
  26. Всероссийское научное общество специалистов по клинической электрофизиологии, аритмологии и кардиостимуляции (ВНОА). Клинические рекомендации по проведению электрофизиологических исследований, катетерной абляции и применению имплантируемых антиаритмических устройств (редакция 2011). М.; 2011. 518 с. Vserossiyskoe nauchnoe obshchestvo spetsialistov po klinicheskoy elektrofiziologii, aritmologii i kardiostimulyatsii (VNOA) [All-Russian Scientific Society of Specialists in Clinical Electrophysiology, Arrhythmology and Cardiac Pacing]. Klinicheskie rekomendatsii po provedeniyu elektrofiziologicheskikh issledovaniy, kateternoy ablyatsii i primeneniyu implantiruemykh antiaritmicheskikh ustroystv (redaktsiya 2011) [Clinical guidelines on electrophysiological assessment, catheter ablation and the use of implanted anti-arrhythmic devices]. Moscow; 2011. 518 p. (in Russian).
  27. European Heart Rhythm Association; European Association for Cardio-Thoracic Surgery; Camm AJ, Kirchhof P, Lip GY, Schotten U, Savelieva I, Ernst S, Van Gelder IC, Al-Attar N, Hindricks G, Prendergast B, Heidbuchel H, Alfieri O, Angelini A, Atar D, Colonna P, De Caterina R, De Sutter J, Goette A, Gorenek B, Heldal M, Hohloser SH, Kolh P, Le Heuzey JY, Ponikowski P, Rutten FH. Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC). Eur Heart J. 2010;31(19):2369–429.
  28. Eguchi K, Ohtaki E, Matsumura T, Tanaka K, Tohbaru T, Iguchi N, Misu K, Asano R, Nagayama M, Sumiyoshi T, Kasegawa H, Hosoda S. Pre-operative atrial fibrillation as the key determinant of outcome of mitral valve repair for degenerative mitral regurgitation. Eur Heart J. 2005;26(18):1866–72.
  29. cardiolog.org [Internet]. Available from: http://cardiolog.org/cardiohirurgia/51-xirurg i c heskaj a -aritmo logi j a /211-xi rur -gicheskoe-lechenie-ma.html?start=1
  30. Schaff HV, Dearani JA, Daly RC, Orszulak TA, Danielson GK. Cox-Maze procedure for atrial fibrillation: Mayo Clinic experience. Semin Thorac Cardiovasc Surg. 2000;12(1):30–7.
  31. Cox JL. Intraoperative options for treating atrial fibrillation associated with mitral valve disease. J Thorac Cardiovasc Surg.
  32. ;122(2):212–5.
  33. Гендлин ГЕ, Самсонова ЕВ, Бухало ОВ. Методики исследования качества жизни у больных хронической недостаточностью кровообращения. Сердечная недостаточность. 2000;1(2):74–80. Gendlin GE, Samsonova EV, Bukhalo OV. Metodiki issledovaniya kachestva zhizni u bol'nykh khronicheskoy nedostatochnost'yu krovoobrashcheniya [Methods for evaluating quality of life in patients with chronic blood circulation insufficiency]. Serdechnaya nedostatochnost' [Heart Failure]. 2000;1(2):74–80 (in Russian).
  34. Орлов ВА, Гиляревский СР. Проблемы изучения качества жизни в современной медицине. М.: Союзмединформ; 1992. 65 с. Orlov VA, Gilyarevskiy SR. Problemy izucheniya kachestva zhizni v sovremennoy meditsine [Issues of study of quality of life in modern medicine]. Moscow: Soyuzmedinform; 1992. 65 p. (in Russian).
  35. Либис РА, Коц ЯИ, Агеев ФТ, Мареев ВЮ. Качество жизни как критерий успешной терапии больных хронической сердечной недостаточностью. Русский медицинский журнал. 1999;7(2):84–7. Libis RA, Kots YaI, Ageev FT, Mareev VYu. Kachestvo zhizni kak kriteriy uspeshnoy terapii bol'nykh khronicheskoy serdechnoy nedostatochnost'yu [Quality of life as an assessment tool to evaluate the effect of chronic heart failure treatment]. Russkiy meditsinskiy zhurnal [Russian Medical Journal]. 1999;7(2):84–7 (in Russian).
  36. Guyatt G, Feeny D, Patrick D. Issues in quality-of-life measurement in clinical trials. Control Clin Trials. 1991;12(4 Suppl):81S–90S.
  37. Rector TS, Tschumperlin LK, Kubo SH, Bank AJ, Francis GS, McDonald KM, Keeler CA, Silver MA. Use of the Living With Heart Failure questionnaire to ascertain patients' perspectives on improvement in quality of life versus risk of drug-induced death. J Card
  38. Fail. 1995;1(3):201–6.
  39. Ishiyama T, Morita Y, Toyama S, Yamagami T, Tsukamoto N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn Heart J. 1976;17(1):32–42.
  40. Rector TS, Kubo SH, Cohn JN. Patients self-assessment of their congestive heart failure. Part 2: content, reliability and validity of a new measure, the Minnesota living with heart failure questionnaire. Heart Fail. 1987;10:198–209.
  41. Трофимов НА, Медведев АП, Бабокин ВЕ, Жамлиханов НХ, Драгунов АГ, Гартфельдер МВ, Николаева ОВ, Драгунова МВ. Эффективность оперативного лечения митральной недостаточности с фибрилляцией предсердий неишемической
  42. этиологии. Медицинский альманах. 2014;(5):165–9. Trofimov NA, Medvedev AP, Babokin VE, Zhamlikhanov NKh, Dragunov AG, Gartfel'der MV, Nikolaeva OV, Dragunova MV. Effektivnost' operativnogo lecheniya mitral'noy nedostatochnosti s fibrillyatsiey predserdiy neishemicheskoy etiologii [The effectiveness of surgical treatment of mitral insufficiency with atrial fibrillation non-ischemic etiology]. Meditsinskiy al'manakh [Medical Almanac]. 2014;(5):165–9 (in Russian).
  43. Гланц С. Медико-биологическая статистика. Пер. с англ. М.: Практика; 1998. 459 с. Glantz S. Biostatistics. Transl. from English. Moscow: Praktika;1998. 459 p. (in Russian).
  44. Боровиков ВП. Statistica: искусство анализа данных на компьютере. 2-е изд. СПб.: Питер; 2003. 688 с. Borovikov VP. Statistica: iskusstvo analiza dannykh na komp'yutere [Statistica: the art of data analysis on the computer]. 2nd ed. Saint Petersburg: Piter; 2003. 688 p. (in Russian).

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2015 Trofimov N.A., Medvedev A.P., Babokin V.E., Demarin O.I., Zhamlikhanov N.K., Dragunov A.G., Gartfelder M.V., Nikolaeva O.V., Dragunova M.V., Eldyrev A.Y., Vladimirova T.N.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies