Email this article Specifics of the perioperative management of the patients undergoing surgery for malignant neoplasms during the COVID-19 pandemic
- Authors: Allakhverdyan A.S.1, Anipchenko A.N.1, Anipchenko N.N.1
-
Affiliations:
- Moscow Regional Research and Clinical Institute (MONIKI)
- Issue: Vol 48 (2020): Supplement 1
- Pages: 68-72
- Section: Journal Articles
- URL: https://almclinmed.ru/jour/article/view/1337
- DOI: https://doi.org/10.18786/2072-0505-2020-48-035
- ID: 1337
Cite item
Full Text
Abstract
Background: The worse prognosis in cancer patients with COVID-19 infection in the context of the pandemic, compared to that in the general population, poses new challenges to ensure the perioperative safety.
Aim: To reduce the risk of infection for cancer patients in the perioperative period and to prevent severe COVID-19.
Materials and methods: During two months of the COVID-19 (from March to April 2020), we performed 158 surgical interventions: 49 for breast cancer, 31 for lung cancer (videothoracoscopic segmental and lobar resections), 12 for stomach cancer (8 distal and 1 proximal laparoscopic subtotal gastric resections, 3 gastrectomies), 16 laparoscopic resections for colorectal cancer, 29 resections with a reconstructive plastic for malignant skin tumors, 21 palliative and diagnostic operations (diagnostic thoracoscopy and laparoscopy, laparoscopic colostomy).
Results: Preventive administration during preparation for surgery (interferon-al-pha2b and low molecular weight heparins) and for suspected infection (antibiotics, low molecular weight heparins and dexamethasone 12 mg/day intravenously) allowed for lower rates of the new coronavirus infection (1.3%) and its severe cases (0%) during surgical treatment of malignant tumors.
Conclusion: Surgical treatment of cancer patients in the context of a new coronavirus infection pandemic should be carried out with strict adherence to anti-epidemic measures.
Keywords
About the authors
A. S. Allakhverdyan
Moscow Regional Research and Clinical Institute (MONIKI)
Author for correspondence.
Email: allakhverdyan@rambler.ru
ORCID iD: 0000-0001-7314-0475
Alexander S. Allakhverdyan - MD, PhD, Professor, Head of Department of Oncology.
61/2 Shchepkina ul., Moscow, 129110, Tel.: +7 (926) 733 69 02
Russian Federation
A. N. Anipchenko
Moscow Regional Research and Clinical Institute (MONIKI)
Email: dottor.alex@mail.ru
ORCID iD: 0000-0002-6543-8498
Aleksey N. Anipchenko - MD, PhD, Head of Surgical Oncology Division.
61/2 Shchepkina ul., Moscow, 129110
Russian FederationN. N. Anipchenko
Moscow Regional Research and Clinical Institute (MONIKI)
Email: dottor.na@gmail.com
ORCID iD: 0000-0002-5386-1336
Natalya N. Anipchenko - MD, PhD, Associate Professor, Chair of Anesthesiology and Reanimation, Postgraduate Training Faculty.
61/2 Shchepkina ul., Moscow, 129110
Russian FederationReferences
- Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, Zhang L, Fan G, Xu J, Gu X, Cheng Z, Yu T, Xia J, Wei Y, Wu W, Xie X, Yin W, Li H, Liu M, Xiao Y, Gao H, Guo L, Xie J, Wang G, Jiang R, Gao Z, Jin Q, Wang J, Cao B. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497-506. doi: 10.1016/S0140-6736(20)30183-5.
- Moletta L, Pierobon ES, Capovilla G, Costanti-ni M, Salvador R, Merigliano S, Valmasoni M. International guidelines and recommendations for surgery during Covid-19 pandemic: A Systematic Review. Int J Surg. 2020;79:180-8. doi: 10.1016/j.ijsu.2020.05.061.
- Liang W, Guan W, Chen R, Wang W, Li J, Xu K, Li C, Ai Q, Lu W, Liang H, Li S, He J. Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China. Lancet Oncol. 2020;21(3): 335-7. doi: 10.1016/S1470-2045(20)30096-6.
- Kamboj M, Sepkowitz KA. Nosocomial infections in patients with cancer. Lancet Oncol. 2009; 10(6):589-97. doi: 10.1016/S1470-2045(09)70069-5.
- Kamarajah SK, Markar SR, Singh P, Griffiths EA; Oesophagogastric Anastomosis Audit Group. The influence of the SARS-CoV-2 pandemic on esophagogastric cancer services: an international survey of esophagogastric surgeons. Dis Esophagus. 2020;33(7):doaa054. doi: 10.1093/dote/doaa054.
- Epidemiology Working Group for NCIP Epidemic Response, Chinese Center for Disease Control and Prevention. [The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China]. Zhonghua Liu Xing Bing Xue Za Zhi. 2020;41(2):145-51. Chinese. doi: 10.3760/cma.j.issn.0254-6450.2020.02.003.
- Brindle ME, Gawande A. Managing COVID-19 in Surgical Systems. Ann Surg. 2020;272(1):e1-2. doi: 10.1097/SLA.0000000000003923.
- Yeo D, Yeo C, Kaushal S, Tan G. COVID-19 and the General Surgical Department - Measures to Reduce Spread of SARS-COV-2 Among Surgeons. Ann Surg. 2020;272(1):e3-4. doi: 10.1097/SLA.0000000000003957.
- Scalea JR. The Distancing of Surgeon From Patient in the Era of COVID-19: Bring on the Innovation. Ann Surg. 2020;272(1):e18-9. doi: 10.1097/SLA.0000000000003962.
- Heffernan DS, Evans HL, Huston JM, Clar-idge JA, Blake DP, May AK, Beilman GS, Barie PS, Kaplan LJ. Surgical Infection Society Guidance for Operative and Peri-Operative Care of Adult Patients Infected by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Surg Infect (Larchmt). 2020;21(4):301-8. doi: 10.1089/sur.2020.101.
- Министерство здравоохранения Российской Федерации. Временные методические рекомендации: профилактика, диагностика и лечение новой коронавирусной инфекции (COVID-19) [Интернет]. Версия 6 (28.04.2020). Доступно на: https://static-1.rosminzdrav.ru/system/attachments/attaches/000/050/122/original/28042020_MR_COVID-19_v6.pdf.
- Министерство здравоохранения Российской Федерации. Временные методические рекомендации: профилактика, диагностика и лечение новой коронавирусной инфекции (COVID-19) [Интернет]. Версия 7 (03.06.2020). Доступно на: https://static-0.rosminzdrav.ru/system/attachments/attaches/000/050/584/original/03062020_%D0%9CR_COVID-19_v7.pdf.
Supplementary files
