THE BIOANTIOXIDANTS (PART 1)

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Abstract

Based on the analysis of the latest scientific data, the paper suggests synthetic classification of known bioantioxidants, peculiarities of their structure and functioning. Enzymatic, phenolic antioxidants, and enzyme mimetics are described in this part of the
review.

About the authors

S. V. Gudkov

Institute of Theoretical and Experimental Biophysics of RAS
Pushchino State Scientific Institute
A.M. Prokhorov General Physics Institute of RAS

Author for correspondence.
Email: s_makariy@rambler.ru
PhD, leading scientific worker, Laboratory of Isotopic Investigation, ITEB of RAS Россия

V. I. Bruskov

Institute of Theoretical and Experimental Biophysics of RAS
Pushchino State Scientific Institute

Email: fake@neicon.ru
PhD, Professor, Head of the Laboratory of Isotopic Investigations, ITEB of RAS Россия

A. V. Kulikov

Institute of Theoretical and Experimental Biophysics of RAS

Email: fake@neicon.ru

PhD, Scientific Secretary, ITEB of RAS

Россия

A. G. Bobylev

Institute of Theoretical and Experimental Biophysics of RAS

Email: fake@neicon.ru

PhD, senior scientific worker, Laboratory of Structure and Functions of Muscular Proteins, ITEB of RAS

Россия

D. A. Kulikov

Institute of Theoretical and Experimental Biophysics of RAS
Moscow Regional Research and Clinical Institute

Email: fake@neicon.ru
PhD, senior scientific worker, Laboratory of Medical and Physical Investigations, MONIKI Россия

A. V. Molochkov

Moscow Regional Research and Clinical Institute

Email: fake@neicon.ru
MD, PhD, Professor, Deputy Director on science, educational work and international relations, MONIKI Россия

References

  1. Зенков Н.К., Ланкин В.З., Меньщикова Е.Б. Окислительный стресс: биохимический и патофизиологический аспекты. М.: МАИК «Наука/Интерпериодика»; 2001. [Zenkov N.K., Lan-kin V.Z., Men'shchikova E.B. Oxidative stress: biochemical and pathophysiological aspects. Moscow: MAIK «Nauka/Interperiodika»; 2001 (in Russian)].
  2. Зенков Н.К., Кандалинцева Н.В., Ланкин В.З., Меньщикова Е.Б., Просенко А.Е. Фенольные биоантиоксиданты. Новосибирск: СО РАМН; 2003. [Zenkov N.K., Kandalintseva N.V., Lankin V.Z., Men’shchikova E.B., Prosenko A.E. Phenolic bioantioxidants. Novosibirsk: SO RAMN; 2003 (in Russian)].
  3. Костюк В.А. , Потапович А.И. Биорадикалы и биоантиоксиданты. Минск: Издательство БГУ; 2004. [Kostyuk V.A., Potapovich A.I. Bioradicals and bioantioxidants. Minsk: Izdate’lstvo BGU; 2004 (in Russian)].
  4. Барабой В.А. Биоантиоксиданты. M.: Книга плюс; 2006. [Baraboy V.A. Bioantioxidants. Moscow: Kniga plyus; 2006 (in Russian)].
  5. Меньщикова Е.Б., Ланкин В.З., Зенков Н.К., Бондарь И.А., Круговых Н.Ф., Труфакин В.А. Окислительный стресс. Прооксиданты и антиоксиданты. M.: Слово; 2006. [Men’shchikova E.B., Lankin V.Z., Zenkov N.K., Bondar’ I.A., Krugovykh N.F., Trufakin V.A. Oxidative stress. Pro-oxidants and antioxidants. Moscow: Slovo; 2006 (in Russian)].
  6. Агабейли Р.А. Биоантиоксиданты: роль в генетической устойчивости и охране биоразнообразия. Баку: Элм; 2008. [Agabeyli R.A. Bioantioxidants: role in genetic stability and preservation of biovariety. Baku: Elm; 2008 (in Russian)].
  7. Попова Н.Р., Гудков С.В., Брусков В.И. Природные пуриновые соединения как радиозащитные средства. Радиационная биология. Радиоэкология 2014;54(1):38-49. [Popova N.R., Gudkov S.V., Bruskov V.I. Natural purine compounds as radioprotective agents. Radiatsionnaya biologiya. Radioekologiya 2014;54(1): 38-49 (in Russian)].
  8. Chernikov A.V., Bruskov V.I., Gudkov S.V. Heat-induced formation of nitrogen oxides in water. J Biol Phys 2013;39(4):687-99.
  9. Bruskov V.I., Karp O.E., Garmash S.A., Shtarkman I.N., Chernikov A.V., Gudkov S.V. Prolongation of oxidative stress by long-lived reactive protein species induced by X-ray radiation and their genotoxic action. Free Radic Res 2012;46(10):1280-90.
  10. Гудков С.В., Карп О.Э., Гармаш С.А., Иванов В.Е., Черников А.В., Манохин А.А., Асташев М.Е., Ягужинский Л.С., Брусков В.И. Образование активных форм кислорода в воде под воздействием видимого и инфракрасного излучения в полосах поглощения молекулярного кислорода. Биофизика 2012;57(1):5-13. [Gudkov S.V., Karp O.E., Garmash S.A., Ivanov V.E., Chernikov A.V., Manokhin A.A., Astashev M.E., Yaguzhinskiy L.S., Bruskov V.I. Production of reactive oxygen forms in water under the influence of visual and infra-red radiation in lines of the molecular oxygen absorption. Biofizika 2012;57(1):5-13 (in Russian)].
  11. Gudkov S.V., Bruskov V.I., Astashev M.E., Chernikov A.V., Yaguzhinsky L.S., Zakharov S.D. Oxygen-dependent autooscillations of water luminescence triggered by the 1264 nm radiation. J Phys Chem B 2011;115(23):7693-8.
  12. Гудкова О.Ю., Гудков С.В., Гапеев А.Б., Брусков В.И., Рубаник А.В., Чемерис Н.К. Исследование механизмов образования активных форм кислорода в водных растворах под действием импульсного электромагнитного излучения крайне высоких частот с большой пиковой мощностью. Биофизика 2005; 50(5):773-9. [Gudkova O.Yu., Gudkov S.V., Gapeev A.B., Bruskov V.I., Rubanik A.V., Chemeris N.K. Studying the mechanisms of the reactive oxygen forms production in aqueous solutions under the influence of impulse electromagnetic radiation of extremely high frequencies with large peak power. Biofizika 2005;50(5):773-9 (in Russian)].
  13. McCord J.M., Fridovich I. Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J Biol Chem 1969; 244(22):6049-55.
  14. Bafana A., Dutt S., Kumar S., Ahuja P.S. Superoxide dismutase: an industrial perspective. Crit Rev Biotechnol 2011;31(1):65-76.
  15. Поберезкина Н.Е., Лосинская Л.Ф. Биологическая роль супероксиддисмутазы. Украинский биохимический журнал 1989; 61(2):14-27. [Poberezkina N.E., Losinskaya L.F. Biological role of super-peroxide-dismutase. Ukrainskiy biokhimicheskiy zhurnal 1989;61(2):14-27 (in Russian)].
  16. Никольская Е.А., Синявская О.И. Каталазы, выделяемые микроорганизмами. Микробиология 1984;46(4):83-93. [Nikolskaya E.A., Sinyavskaya O.I. Catalases excreted by microorganisms. Mikrobiologiya 1984;46(4):83-93 (in Russian)].
  17. Fernandez V., Videla L.A. Biochemical aspects of cellular antioxidant systems. Biol Res 1996;29(2):177-82.
  18. Mills G.C. Hemoglobin catabolism. I. Glutathione peroxidase, an erythrocyte enzyme which protects hemoglobin from oxidative breakdown. J Biol Chem 1957;229(1):189-97.
  19. Логинов А.С., Матюшин Б.Н., Ткачев В.Д., Якимчук Г.Н. Новый подход к диагностике холестаза по активности медьсодержащих ферментов. Терапевтический архив 1993;(2):34-6. [Loginov A.S., Matyushin B.N., Tkachev V.D., Yakimchuk G.N. A new approach to cholestasis diagnosis based on the activity of the copper-containing enzymes. Terapevticheskiy arkhiv 1993;(2): 34-6 (in Russian)].
  20. Pearson W.R. Phylogenies of glutathione transferase families. Methods Enzymol 2005;401:186-204.
  21. Гудков С.В., Брусков В.И. Гуанозин и инозин (рибоксин). Антиоксидантные и радиозащитные свойства. Saarbrücken: Lambert Academic Publishing; 2011. [Gudkov S.V., Bruskov V.I. Guanosine and inosine (riboxin). Antioxidant and radioprotective properties. Saarbrücken: Lambert Academic Publishing; 2011 (in Russian)].
  22. Рогинский В.А. Фенольные антиоксиданты: реакционная способность и эффективность. М.: Наука; 1988. [Roginskiy V.A. Phenolic antioxidants: reactive capacity and effectiveness. Moscow: Nauka; 1988 (in Russian)].
  23. Гудков С.В. Механизмы образования активных форм кислорода под влиянием физических факторов и их генотоксическое действие [диссертация]. Пущино: ИТЭБ РАН; 2012. [Gudkov S.V. The mechanisms of the reactive oxygen species production under the influence of physical factors and their genotoxic activity [dissertation]. Pushchino: ITEB RAS; 2012 (in Russian)].
  24. Кретович В.Л. Биохимия растений. М.: Высшая школа; 1980. [Kretovich V.L. Plant biochemistry. Moscow: Vysshaya shkola; 1980 (in Russian)].
  25. Terao J., Mukai R. Prenylation modulates the bioavailability and bioaccumulation of dietary flavonoids. Arch Biochem Biophys 2014;pii:S0003-9861(14)00125-8. [Epub ahead of print].
  26. Kumar S., Pandey A.K. Chemistry and biological activities of flavonoids: an overview. ScientificWorldJournal 2013;162750.
  27. Pekmezci D. Vitamin E and immunity. Vitam Horm 2011;86: 179-215.
  28. Evans H., Emerson О., Emerson G. The isolation from wheat germ of an alcohol α-tocopherol. J Biol Chem 1936;113:319-25.
  29. Jiang Q. Natural forms of vitamin E: metabolism, antioxidant, and anti-inflammatory activities and their role in disease prevention and therapy. Free Radic Biol Med 2014;72C:76-90. [Epub ahead of print].
  30. Rahman I. Antioxidant therapeutic advances in COPD. Ther Adv Respir Dis 2008;2(6):351-74.
  31. Salvemini D., Wang Z.Q., Zweier J.L., Samouilov A., Macarthur H., Misko T.P., Currie M.G., Cuzzocrea S., Sikorski J.A., Riley D.P. A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats. Science 1999;286(5438):304-6.
  32. Muscoli C., Sacco I., Alecce W., Palma E., Nisticò R., Costa N., Clementi F., Rotiroti D., Romeo F., Salvemini D., Mehta J.L. The protective effect of superoxide dismutase mimetic M40401 on balloon injury-related neointima formation: role of the lectin-like oxidized low-density lipoprotein receptor-1. J Pharmacol Exp Ther 2004;311:44-50.
  33. Thompson J.S., Chu Y., Glass J., Tapp A.A., Brown S.A. The manganese superoxide dismutase mimetic, M40403, protects adult mice from lethal total body irradiation. Free Radic Res 2010;44(5):529-40.
  34. Chatterjee P.K., Patel N.S., Kvale E.O., Brown P.A., Stewart K.N., Mota-Filipe H., Sharpe M.A., Di Paola R., Cuzzocrea S., Thiemermann C. EUK-134 reduces renal dysfunction and injury caused by oxidative and nitrosative stress of the kidney. Am J Nephrol 2004;24(2):165-77.
  35. Sharpe M.A., Ollosson R., Stewart V.C., Clark J.B. Oxidation of nitric oxide by oxomanganese-salen complexes: a new mechanism for cellular protection by superoxide dismutase/catalase mimetics. Biochem J 2002;366(Pt 1):97-107.

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Copyright (c) 2014 Gudkov S.V., Bruskov V.I., Kulikov A.V., Bobylev A.G., Kulikov D.A., Molochkov A.V.

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