ИММУНОЛОГИЧЕСКАЯ ФУНКЦИЯ ИНТЕСТИНАЛЬНОЙ МИКРОФЛОРЫ, ЕЕ НАРУШЕНИЯ И ВОЗМОЖНОСТИ КОРРЕКЦИИ

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В обзоре представлены современные данные, свидетельствующие  о том, что нормальная  микрофлора  играет  важную роль  в развитии  иммунной системы кишечника. Интестинальные микроорганизмы  стимулируют созревание лимфоидного аппарата кишечника, синтез секреторного  иммуноглобулина  А, активизируют фагоцитоз,   стимулируют   систему   цитокинов и интерферонов. Представляет  интерес  обсуждение  информации  о  том, что  феномен  толерантности является наиболее значимым для создания   устойчивого   микробиоценоза.  Для   направленного формирования  или  восстановления нарушенного  микробиоценоза все шире применяют пробиотики. В качестве одного из ключевых требований  к пробиотикам  признано подтверждение полезных свойств каждого штамма пробиотической  культуры в контролируемых клинических исследованиях.

Об авторах

Н. И. Урсова

Московский областной научно-исследовательский клинический институт имени М.Ф. Владимирского

Автор, ответственный за переписку.
Email: ursovan@mail.ru
Урсова Наталия Игоревна –  доктор медицинских наук, профессор, руководитель педиатрического отделения, заведующая кафедрой педиатрии факультета усовершенствования врачей, главный педиатр Министерства здравоохранения Московской области Россия

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