Email this article NEUROCOGNITIVE SCREENING IN ISCHEMIC HEART DISEASE PATIENTS WHO NEED SURGICAL TREATMENT
- Authors: Litvinenko M.A.1, Kotov A.S.1, Romanov S.V.1, Terpigorev S.A.1, Kabanova T.G.1, Borisova M.N.1
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Affiliations:
- Moscow Regional Research and Clinical Institute (MONIKI)
- Issue: No 39 (2015)
- Pages: 51-55
- Section: ARTICLES
- URL: https://almclinmed.ru/jour/article/view/218
- DOI: https://doi.org/10.18786/2072-0505-2015-39-51-55
- ID: 218
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Abstract
Background: Coronary artery atherosclerosis is one of the main causes of ischemic heart disease. Formation of chronic vascular brain insufficiency in ischemic heart disease has a complex pathogenesis and can be related to a lower cardiac output. Occurrence and progression of neurodegenerative process in such patients can manifest by significant cognitive impairment deteriorating their quality of life and leading to social disadaptation.
Aim: To assess neuropsychological functions in patients with coronary artery atherosclerosis and to identify potential risk factors predisposing to the development of cognitive and neurological impairment.
Materials and methods: The study included 30 patients with stable angina requiring coronary surgical interventions and 25 patients with acute coronary syndrome. The patient age was 57.3 ± 1.8 and 58.3 ± 10.9 years, respectively. In 15 of cases, acute coronary syndrome was associated with ST elevation on ECG and in 10 of cases no ST elevation was noted. All patients were seen by a neurologist and underwent neuropsychological testing. The patients were divided into two groups: those in need of a stent placement (group 1), those in need of coronary artery bypass grafting (group 2) and those with acute coronary syndrome ( group 3).
Results: Assessment of cognitive functions with a Montreal cognitive assessment scale gave the following results: the total mean score in the group 1 was 24.3 ± 0.5, in the group 2, 26.3 ± 0.5 (normal at least 26), the difference between the groups being statistically significant (p = 0.0172). Cognitive impairment was more frequently found in acute coronary syndrome patients with ST elevation, who had more severe cardiac abnormalities, compared to those with acute coronary syndrome without ST elevation.
Conclusion: Most patients with clinically significant atherosclerosis of coronary arteries have mild and moderate cognitive disorders, that indicate the importance of a neuropsychological screening for early detection of cognitive and neurological impairment in such patients.
About the authors
M. A. Litvinenko
Moscow Regional Research and Clinical Institute (MONIKI)
Email: fake@neicon.ru
Postgraduate Student, Chair of Neurology, Postgraduate Training Faculty
РоссияA. S. Kotov
Moscow Regional Research and Clinical Institute (MONIKI)
Author for correspondence.
Email: alex-013@yandex.ru
MD, PhD, Professor, Chair of Neurology, Postgraduate Training Faculty; Deputy in Research of the Head of Department of Pediatric Neurology
РоссияS. V. Romanov
Moscow Regional Research and Clinical Institute (MONIKI)
Email: fake@neicon.ru
Postgraduate Student, Chair of Neurology, Postgraduate Training Faculty
РоссияS. A. Terpigorev
Moscow Regional Research and Clinical Institute (MONIKI)
Email: fake@neicon.ru
MD, PhD, Head of Department for Occupational Diseases and Medical and Labour Expert Commission
РоссияT. G. Kabanova
Moscow Regional Research and Clinical Institute (MONIKI)
Email: fake@neicon.ru
PhD, Research Fellow, Department for Occupational Diseases andMedical and Labour Expert Commission
РоссияM. N. Borisova
Moscow Regional Research and Clinical Institute (MONIKI)
Email: fake@neicon.ru
PhD, Senior Research Fellow, Department of Pediatric Neurology
РоссияReferences
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