Email this article Non-invasive assessment of skin microcirculation in patients with COVID-19: three clinical cases
- Authors: Glazkova P.A.1, Kulikov D.A.1, Rogatkin D.A.1, Zhuravlev O.R.1, Shekhyan G.G.1, Glazkov А.A.1, Kozlova K.A.1, Terpigorev S.A.1
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Affiliations:
- Moscow Regional Research and Clinical Institute (MONIKI)
- Issue: Vol 48 (2020): Supplement 1
- Pages: 27-31
- Section: Journal Articles
- URL: https://almclinmed.ru/jour/article/view/1345
- DOI: https://doi.org/10.18786/2072-0505-2020-48-037
- ID: 1345
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Abstract
Currently, there is enough data to suggest a significant role of microcirculation abnormalities in the pathophysiology of COVID-19. However, no clinical studies on noninvasive assessment of blood microcirculation in patients with the new coronavirus infection have been performed. We measured skin microcirculation by laser Doppler flowmetry in the thermal and inspiratory gasp tests in 3 patients with various courses of COVID-19. A decrease in the skin microcirculation reactivity was found in a patient with a more severe course of coronavirus infection. We believe that assessment of skin microcirculation could become a promising tool for the development of new diagnostic approaches and in future of new treatments for patients with coronavirus infection, as well as for identification of patient categories with a high risk of its severe course. Further studies are required to evaluate the clinical applicability of laser Doppler flowmetry for assessment of skin microcirculation in patients with COVID-19.
About the authors
P. A. Glazkova
Moscow Regional Research and Clinical Institute (MONIKI)
Author for correspondence.
Email: polinikul@mail.ru
ORCID iD: 0000-0002-8830-7503
Polina A. Glazkova - Research Fellow, Laboratory of Medical and Physical Research.
61/2-8 Shchepkina ul., Moscow, 129110, Tel.: +7 (495) 681 89 84
Russian FederationD. A. Kulikov
Moscow Regional Research and Clinical Institute (MONIKI)
Email: fake@neicon.ru
ORCID iD: 0000-0002-4273-8295
Dmitry A. Kulikov - MD, PhD, Academic Secretary, Associate Professor, Chair of Endocrinology, Postgraduate Training Faculty.
61/2 Shchepkina ul., Moscow, 129110
Russian FederationD. A. Rogatkin
Moscow Regional Research and Clinical Institute (MONIKI)
Email: fake@neicon.ru
ORCID iD: 0000-0002-7755-308X
Dmitry A. Rogatkin -PhD (in Engineering), Head of Laboratory of Medical and Physical Research.
61/2 Shchepkina ul., Moscow, 129110
Russian FederationO. R. Zhuravlev
Moscow Regional Research and Clinical Institute (MONIKI)
Email: fake@neicon.ru
ORCID iD: 0000-0002-8457-2537
Oleg R. Zhuravlev - Junior Research Fellow, Department of Hematology and Immunotherapy.
61/2 Shchepkina ul., Moscow, 129110 Russian FederationG. G. Shekhyan
Moscow Regional Research and Clinical Institute (MONIKI)
Email: fake@neicon.ru
ORCID iD: 0000-0003-0442-644X
Grant G. Shekhyan - MD, PhD, Leading Research Fellow, Department of Cardiology; Professor, Chair of Internal Diseases, Postgraduate Training Faculty.
61/2 Shchepkina ul., Moscow, 129110
Russian FederationА. A. Glazkov
Moscow Regional Research and Clinical Institute (MONIKI)
Email: fake@neicon.ru
ORCID iD: 0000-0001-6122-0638
Alexey A. Glazkov - Research Fellow, Laboratory of Medical and Physical Research.
61/2 Shchepkina ul., Moscow, 129110
Russian FederationK. A. Kozlova
Moscow Regional Research and Clinical Institute (MONIKI)
Email: fake@neicon.ru
ORCID iD: 0000-0003-4146-930X
Ksenia A. Kozlova - Laboratory Technician, Department of Experimental and Clinical Research.
61/2 Shchepkina ul., Moscow, 129110
Russian FederationS. A. Terpigorev
Moscow Regional Research and Clinical Institute (MONIKI)
Email: fake@neicon.ru
ORCID iD: 0000-0001-5444-5943
Stanislav A. Terpigorev - MD, PhD, Head of Department of Occupational Pathology and Medical Examination; Professor, Chair of Internal Diseases, Postgraduate Training Faculty.
61/2 Shchepkina ul., Moscow, 129110
Russian FederationReferences
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