Almanac of Clinical MedicineAlmanac of Clinical MedicineАльманах клинической медицины2072-05052587-9294Moscow Regional Research and Clinical Institute (MONIKI)37910.18786/2072-0505-2015-0-36-744-750ARTICLESОРИГИНАЛЬНЫЕ СТАТЬИConfocal laser endomicroscopy in the diagnosis of colorectal diseases: image interpretation criteriaКонфокальная лазерная эндомикроскопия в диагностике заболеваний толстой кишки: критерии интерпретации изображенийShcherbakovP. L.ЩербаковП. Л.
Russian Federation

Shcherbakov Petr L. – MD, PhD, Professor, Head of Hospital.

1A Malaya Pirogovskaya ul., Moscow, 119435, Russian Federation. Tel.: +7 (985) 764 54 43. E-mail: petersh@rcpcm.org

Щербаков Петр Леонидович – доктор медицинских наук, профессор, заведующий стационаром.

119435, г. Москва, ул. Малая Пироговская, 1а, Российская Федерация. Тел.: +7 (985) 764 54 43. E-mail: petersh@rcpcm.orgpetersh@rcpcm.orgKirovaM. V.КироваМ. В.
Russian Federation

Kirova Marina V. – MD, Senior Research Fellow

Кирова Марина Владимировна – старший научный сотрудник

Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, MoscowФедеральный научно-клинический центр физико-химической медицины Федерального медико-биологического агентства, МоскваMoscow Clinical Research and Practical Center, Moscow Healthcare Department, MoscowМосковский клинический научно-практический центр ДЗМ, Москва150920164467447502909201629092016Copyright ©; 2016, Shcherbakov P.L., Kirova M.V.Copyright ©; 2016, Щербаков П.Л., Кирова М.В.2016Shcherbakov P.L., Kirova M.V.Щербаков П.Л., Кирова М.В.https://creativecommons.org/licenses/by/4.0https://almclinmed.ru/jour/article/view/379

Confocal laser endomicroscopy is a rapidly emerging area of gastroenterology that bridges endoscopy and histological examination. This newest technique has enabled endoscopists to assess the microstructure of gastrointestinal mucosa in vivo during the endoscopic procedure ("virtual biopsy"), and has stimulated growing interest to its application in clinical practice. During colonoscopy, the use of confocal laser endomicroscopy is justified for assessment of post-resection margins after excision of epithelial neoplasms, for differential diagnosis of polyps and assessment of the colon in patients with inflammatory bowel disorders. This article presents the interpretation criteria of confocal images in various colon diseases and the published data on the diagnostic value of the method.

Конфокальная лазерная эндомикроскопия – быстро развивающееся направление в гастроэнтерологии, представляющее собой мост между эндоскопией и гистологическим исследованием. Эта новейшая  технология  обеспечила  возможность изучения микроструктуры слизистой оболочки  желудочно-кишечного  тракта  in vivo во время  проведения эндоскопического  исследования («виртуальная биопсия») и вызывает все больший интерес к применению в клинической практике. При исследовании  толстой кишки применение конфокальной эндомикроскопии оправдано для  оценки  краев  резекции  после удаления эпителиальных образований, для дифференциальной диагностики полипов и оценки состояния толстой кишки у больных с воспалительными  заболеваниями кишечника. В  статье представлены критерии интерпретации конфокальных изображений  при  различных  заболеваниях толстой кишки и данные литературы по диагностической ценности метода.

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