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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Almanac of Clinical Medicine</journal-id><journal-title-group><journal-title xml:lang="en">Almanac of Clinical Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Альманах клинической медицины</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2072-0505</issn><issn publication-format="electronic">2587-9294</issn><publisher><publisher-name xml:lang="en">Moscow Regional Research and Clinical Institute (MONIKI)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">272</article-id><article-id pub-id-type="doi">10.18786/2072-0505-2015-38-90-94</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>LECTURE</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ЛЕКЦИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">PULMONARY EMBOLISM: ISSUES OF CLINICAL MANIFESTATION, DIAGNOSTICS AND THERAPY</article-title><trans-title-group xml:lang="ru"><trans-title>ТРОМБОЭМБОЛИЯ ЛЕГОЧНОЙ АРТЕРИИ (ВОПРОСЫ КЛИНИКИ, ДИАГНОСТИКИ И ТЕРАПИИ)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gurevich</surname><given-names>M. A.</given-names></name><name xml:lang="ru"><surname>Гуревич</surname><given-names>М. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD, Professor, Department of Internal Diseases, Postgraduate Medical Faculty</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор, профессор кафедры терапии факультета усовершенствования врачей</p></bio><email>magurevich@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Moscow Regional Research and Clinical Institute (MONIKI)</institution></aff><aff><institution xml:lang="ru">ГБУЗ МО «Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2015-05-15" publication-format="electronic"><day>15</day><month>05</month><year>2015</year></pub-date><issue>38</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>90</fpage><lpage>94</lpage><history><date date-type="received" iso-8601-date="2016-02-22"><day>22</day><month>02</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-02-22"><day>22</day><month>02</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2015, Gurevich M.A.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2015, Гуревич М.А.</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="en">Gurevich M.A.</copyright-holder><copyright-holder xml:lang="ru">Гуревич М.А.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://almclinmed.ru/jour/article/view/272">https://almclinmed.ru/jour/article/view/272</self-uri><abstract xml:lang="en"><p>In this lecture the author highlights various aspects of pulmonary thromboembolism (PTE) with evidence-based data and his own observations for many years. Risk factors for PTE and deep vein thrombosis of lower extremities are described in details, as well as clinical manifestations of PTE depending on localization of an embolus in pulmonary arterial tree. Current diagnostic approached to PTE are presented, including perfusion scintigraphy, pulmonary angiography, ileocavagraphy, measurement of D-dimer levels. Methods of surgical and medical treatment, including their indications, are described.</p></abstract><trans-abstract xml:lang="ru"><p>В статье-лекции на основании данных доказательной медицины и многолетних собственных наблюдений автор подробно освещает различные аспекты тромбоэмболии легочной артерии (ТЭЛА). Детально описаны факторы риска возникновения ТЭЛА и тромбоза глубоких вен нижних конечностей, а также клиническая картина ТЭЛА в зависимости от локализации эмбола в системе легочных артерий. Представлена современная диагностика ТЭЛА, включая перфузионную сцинтиграфию, ангиопульмонографию, илеокаваграфию, определение концентрации Д-димера. Описаны методы хирургической и консервативной терапии, показания к ним.</p></trans-abstract><kwd-group xml:lang="en"><kwd>pulmonary thromboembolism</kwd><kwd>deep vein thrombosis of lower extremities</kwd><kwd>clinical manifestations</kwd><kwd>methods of instrumental assessment</kwd><kwd>treatment</kwd><kwd>D-dimer</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>тромбоэмболия легочной артерии</kwd><kwd>тромбоз глубоких вен нижних конечностей</kwd><kwd>клинические проявления</kwd><kwd>методы инструментальной диагностики</kwd><kwd>терапия</kwd><kwd>Д-димер</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Яковлев ВБ. Тромбоэмболия легочной артерии. Диагностика, лечение, профилактика. Русский медицинский журнал. 1998;(1):1036–47. Yakovlev VB. 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