Almanac of Clinical MedicineAlmanac of Clinical MedicineАльманах клинической медицины2072-05052587-9294Moscow Regional Research and Clinical Institute (MONIKI)25910.18786/2072-0505-2015-37-111-117GYNECOLOGYГИНЕКОЛОГИЯFACTORS OF WOMEN’S HEALTH FROM THE PERSPECTIVE OF REPRODUCTIVE AGEING AND RISK OF CARDIOVASCULAR DISORDERSФАКТОРЫ ЖЕНСКОГО ЗДОРОВЬЯ С ТОЧКИ ЗРЕНИЯ СТАРЕНИЯ РЕПРОДУКТИВНОЙ СИСТЕМЫ И РИСКА РАЗВИТИЯ СЕРДЕЧНО-СОСУДИСТЫХ ЗАБОЛЕВАНИЙLopatinaO. V.ЛопатинаО. В.
Russian Federation

Postgraduate Student

аспирант

BalanV. E.БаланВ. Е.
Russian Federation

MD, PhD, Professor, Head of Research and Consultative Department

д-р мед. наук, профессор, руководитель научно-консультативного отделения

balanmed@gmail.comTkachevaO. N.ТкачеваО. Н.
Russian Federation

MD, PhD, Professor, First Deputy Director on Research and Medical Care

д-р мед. наук, профессор, первый заместитель директора по научной и лечебной работе

SharashkinaN. V.ШарашкинаН. В.
Russian Federation

PhD, Senior Research Fellow

канд. мед. наук, ст. науч. сотр

Zhuravel'A. S.ЖуравельА. С.
Russian Federation

Postgraduate Student

аспирант

Moscow Regional Scientific Research Institute for Obstetrics and GynecologyГБУЗ МО «Московский областной научно-исследовательский институт акушерства и гинекологии»State Research Center for Preventive MedicineФГБУ «Государственный научно-исследовательский центр профилактической медицины» Минздрава России15032015371111172202201622022016Copyright ©; 2015, Lopatina O.V., Balan V.E., Tkacheva O.N., Sharashkina N.V., Zhuravel' A.S.Copyright ©; 2015, Лопатина О.В., Балан В.Е., Ткачева О.Н., Шарашкина Н.В., Журавель А.С.2015Lopatina O.V., Balan V.E., Tkacheva O.N., Sharashkina N.V., Zhuravel' A.S.Лопатина О.В., Балан В.Е., Ткачева О.Н., Шарашкина Н.В., Журавель А.С.https://creativecommons.org/licenses/by/4.0https://almclinmed.ru/jour/article/view/259

Prevalence of cardiovascular abnormalities in women of reproductive age is not high. However, it is during this period that the risk factors of cardiovascular disorders are being formed. They include obesity, arterial hypertension, dyslipidemia, insulin resistance, diabetes mellitus, etc. The review demonstrates the link between cardiovascular risk factors and obstetric and gynecological  isorders, starting from menarche and ending up with menopause. Degree of vascular ageing is considered to be one of indicators of age-related changes of cardiovascular system. There is an association between markers of ageing, such as length of telomers and telomerase activity, and estrogen deficiency.

В репродуктивном возрасте распространенность сердечно-сосудистой патологии у женщин невелика. Но в этот период происходит формирование факторов риска развития сердечно-сосудистых заболеваний. К ним относят ожирение, артериальную гипертонию, дислипидемию, инсулинорезистентность, сахарный диабет и др. В обзоре показана связь факторов риска сердечно-сосудистых заболеваний с акушерской и гинекологической патологией начиная с менархе и заканчивая постменопаузой. Одним из показателей возрастных изменений сердечно-сосудистой системы принято считать степень выраженности старения сосудов. Выявлено наличие ассоциации между маркерами старения – длиной теломер и активностью теломеразы – и дефицитом эстрогенов.

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