Almanac of Clinical MedicineAlmanac of Clinical Medicine2072-05052587-9294Moscow Regional Research and Clinical Institute (MONIKI)21110.18786/2072-0505-2015-36-26-28ANALYSIS OF EFFECTIVENESS OF DIFFERENT SURGICAL METHODS AND EARLY POSTOPERATIVE COMPLICATIONS IN PATIENTS WITH PSEUDOEXFOLIATION GLAUCOMADatskikhE. O.marina.datskih@yandex.ruKonovalovaO. S.fake@neicon.ruMal’tsevN. G.fake@neicon.ruTyumen State Medical AcademyTyumen Regional Clinical Hospital No. 1150120153626282102201621022016Copyright © 2015, Datskikh E.O., Konovalova O.S., Mal’tsev N.G.2015<p><strong>Aim: </strong>To study the effectiveness of several surgical methods in patients with pseudoexfoliation glaucoma (PEG); to assess frequency of early postoperative complications.</p><p> </p><p><strong>Materials and methods: </strong>We analyzed hospital medical records of 554 patients with verified diagnosis of PEG; the patients underwent surgical treatment in the State-Financed Health Institution of the Tyumen Region “Regional Clinical Hospital No. 1”.</p><p> </p><p><strong>Results: </strong>The majority of patients were 70 years old (mean age was 67.5 ± 21.5 years old). Types of surgical treatment were as follows: sinus trabeculectomy (STE) with posterior scleral trepanation in 73.1% of the cases (n = 405), non-penetrating deep sclerectomy (NPDS) – in 23.8% (n = 132); STE + posterior scleral trepanation and use of silicone drainage Repegel-1 (STE + drainage) – in 3.1% (n = 17). After primary STE, postoperative complications were found in 20% (n = 31) of the patients; after repeated STE – in 76.8% (n = 119); after STE + drainage – in 3.2% (n = 5). Early postoperative complications of STE were diagnosed in 28% (n = 155) of the patients including hyphema in 45% (n = 70) of cases, postoperative hypertension in 31% (n = 48), absence of filtering bleb in 20% (n = 31) and others in 4% (n = 6) of cases. After repeated STE, early postoperative hypertension</p><p>was found only in patients with hyphema (in 99.2% (n = 118) of cases, p 0,05).</p><p> </p><p><strong>С</strong><strong>onclusion: </strong>Analysis of the results of several surgical methods of treatment for pseudoexfoliation glaucoma demonstrated inefficiency of NPDS; on the contrary, STE and STE + drainage are regarded as methods of choice. Concomitant cardiovascular diseases contribute to the progression of PEG and increase the risk of early postoperative complications.</p>pseudoexfoliation glaucomapseudoexfoliative syndromesinus trabeculectomy with posterior scleral trepanationpenetrating deep sclerectomysinus trabeculectomy with posterior scleral trepanation and use of silicone drainage Repegel-1псевдоэксфолиативная глаукомапсевдоэксфолиативный синдромсинустрабекулэктомия с задней трепанацией склерынепроникающая глубокая склерэктомиясинустрабекулэктомия с задней трепанацией склеры и применением силиконового дренажа Репегель-1[1. Брежнев АЮ, Юрьева ТН. Псевдоэксфолиативная глаукома. В: Егоров ЕА, ред. Глаукома. Национальное руководство. М.: ГЭОТАР-Медиа; 2013. (Brezhnev AYu, Yur’eva TN. Pseudoexfoliation glaucoma. In: Egorov EA, editor. Glaukoma. National guidance. Moscow: GEOTAR-Media; 2013. Russian).][2. Damji KF. Progress in understanding pseudoexfoliation syndrome and pseudoexfoliationassociated glaucoma. Can J Ophthalmol.][2007;42(5):657–8.][3. Grieshaber MC, Flammer J. Blood flow in glaucoma. Curr Opin Ophthalmol. 2005;16(2):79–83.][4. Grodum K, Heijl A, Bengtsson B. Risk of glaucoma in ocular hypertension with and without pseudoexfoliation. Ophthalmology.][2005;112(3):386–90.][5. Mitchell P, Lee AJ, Rochtchina E, Wang JJ. Openangle glaucoma and systemic hypertension: the blue mountains eye study. J Glaucoma. 2004;13(4):319–26.][6. Ritch R, Schlotzer-Schrehardt U, Konstas AG. Why is glaucoma associated with exfoliation syndrome? Prog Retin Eye Res. 2003;22(3): 253–75.][7. Tarkkanen A, Reunanen A, Kivela T. Frequency of systemic vascular diseases in patients with primary open-angle glaucoma and exfoliation glaucoma. Acta Ophthalmol. 2008;86(6):598–602.]