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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Almanac of Clinical Medicine</journal-id><journal-title-group><journal-title xml:lang="en">Almanac of Clinical Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Альманах клинической медицины</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2072-0505</issn><issn publication-format="electronic">2587-9294</issn><publisher><publisher-name xml:lang="en">Moscow Regional Research and Clinical Institute (MONIKI)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">180</article-id><article-id pub-id-type="doi">10.18786/2072-0505-2014-35-94-100</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>LECTURE</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ЛЕКЦИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">RAYNAUD’S PHENOMENON: A MULTIDISCIPLINARY PROBLEM</article-title><trans-title-group xml:lang="ru"><trans-title>СИНДРОМ РЕЙНО КАК МУЛЬТИДИСЦИПЛИНАРНАЯ ПРОБЛЕМА</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Alekperov</surname><given-names>R. T.</given-names></name><name xml:lang="ru"><surname>Алекперов</surname><given-names>Р. Т.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, PhD, Professor, Internal Diseases Department, Postgraduate Medical School;</p><p>Senior Research Associate</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор кафедры терапии факультета усовершенствования врачей; ст. науч. сотр.</p></bio><email>ralekperov@list.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Moscow Regional Research and Clinical Institute (MONIKI)</institution></aff><aff><institution xml:lang="ru">ГБУЗ МО «Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">61/2 Shchepkina ul., Moscow, 129110, Russian Federation&#13;
V.A. Nasonova Research Institute of Rheumatology, Russian Academy of Medical Sciences</institution></aff><aff><institution xml:lang="ru">129110, г. Москва, ул. Щепкина, 61/2, Российская Федерация&#13;
ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">34А Kashirskoe shosse, Moscow, 115522, Russian Federation</institution></aff><aff><institution xml:lang="ru">115522, г. Москва, Каширское шоссе, 34А, Российская Федерация</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2014-10-15" publication-format="electronic"><day>15</day><month>10</month><year>2014</year></pub-date><issue>35</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>94</fpage><lpage>100</lpage><history><date date-type="received" iso-8601-date="2016-02-17"><day>17</day><month>02</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-02-17"><day>17</day><month>02</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2014, Alekperov R.T.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2014, Алекперов Р.Т.</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="en">Alekperov R.T.</copyright-holder><copyright-holder xml:lang="ru">Алекперов Р.Т.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://almclinmed.ru/jour/article/view/180">https://almclinmed.ru/jour/article/view/180</self-uri><abstract xml:lang="en"><p>Raynaud’s phenomenon (RP) is a common medical condition with prevalence in the population about 3–5%. RP is subdivided into primary form manifesting mainly in children and adolescents, and secondary RP affecting elder patients. Secondary RP is frequently associated with systemic rheumatic disorders, endocrine and hematological diseases and certain infections. It also may be due to exogenous factors. Thus, RP is an actual problem in the practice of rheumatologists, pediatric physicians, infectious diseases specialists, hematologists and other medical practitioners. This clinical lecture discusses in detail current approaches to diagnosis and differential diagnosis of RP.</p></abstract><trans-abstract xml:lang="ru"><p>Синдром Рейно широко распространен в популяции: его частота составляет в среднем 3–5%. Он подразделяется на первичный, с  дебютом преимущественно в  детском и  подростковом возрасте, и  вторичный, развивающийся в  более старшей возрастной группе. Вторичный синдром Рейно ассоциируется с  системными ревматическими заболеваниями, эндокринной и  гематологической патологией, отдельными инфекциями. Он также может быть обусловлен экзогенными факторами. В  этой связи данное состояние часто встречается в  практике ревматологов, педиатров, инфекционистов, гематологов и  врачей других специальностей. В  лекции подробно излагаются современные подходы к  диагностике и  дифференциальной диагностике синдрома Рейно.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Raynaud’s phenomenon</kwd><kwd>diagnosis</kwd><kwd>differential diagnosis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>синдром Рейно</kwd><kwd>диагностика</kwd><kwd>дифференциальная диагностика</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Palmer KT, Griffin MJ, Syddall H, Pannett B, Cooper C, Coggon D. 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