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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Almanac of Clinical Medicine</journal-id><journal-title-group><journal-title xml:lang="en">Almanac of Clinical Medicine</journal-title><trans-title-group xml:lang="ru"><trans-title>Альманах клинической медицины</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2072-0505</issn><issn publication-format="electronic">2587-9294</issn><publisher><publisher-name xml:lang="en">Moscow Regional Research and Clinical Institute (MONIKI)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1431</article-id><article-id pub-id-type="doi">10.18786/2072-0505-2021-49-010</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEW ARTICLE</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Contrast-enhanced magnetic resonance imaging in the diagnosis of Meniere’s disease: vague future or tangible reality?</article-title><trans-title-group xml:lang="ru"><trans-title>Магнитно-резонансная томография с контрастным усилением в диагностике болезни Меньера: туманное будущее или осязаемая реальность?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9037-0034</contrib-id><name-alternatives><name xml:lang="en"><surname>Stepanova</surname><given-names>E. A.</given-names></name><name xml:lang="ru"><surname>Степанова</surname><given-names>Е. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><bold>Elena A. Stepanova</bold> – MD, PhD, Chief Research Fellow, Diagnostic Department </p><p><italic>61/2 Shchepkina ul., Moscow, 129110</italic></p></bio><bio xml:lang="ru"><p><bold>Степанова Елена Александровна</bold> – кандидат медицинских наук, главный научный сотрудник диагностического отделения</p><p><italic>129110, г. Москва, ул. Щепкина, 61/2</italic></p></bio><email>stepanovamoniki@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Moscow Regional Research and Clinical Institute (MONIKI)</institution></aff><aff><institution xml:lang="ru">ГБУЗ МО «Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2021-03-30" publication-format="electronic"><day>30</day><month>03</month><year>2021</year></pub-date><volume>49</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>72</fpage><lpage>79</lpage><history><date date-type="received" iso-8601-date="2021-03-15"><day>15</day><month>03</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-03-15"><day>15</day><month>03</month><year>2021</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2021, Stepanova E.A.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2021, Степанова Е.А.</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="en">Stepanova E.A.</copyright-holder><copyright-holder xml:lang="ru">Степанова Е.А.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://almclinmed.ru/jour/article/view/1431">https://almclinmed.ru/jour/article/view/1431</self-uri><abstract xml:lang="en"><p>Meniere's disease is characterized by vertigo, inconsistent hearing loss and progressive deterioration of audiological and vestibular functions. The attacks of Meniere's disease occur without obvious triggers and disrupt social adaptation of patients. Radiation diagnostic methods have not been included into the list of diagnostic criteria by the European Consensus on Diagnosis and Management of Meniere's disease (2018). However, a  number of studies have been published recently that indicate the feasibility of in vivo anatomical identification of endolymphatic hydrops, as the main disease substrate seen using contrast-enhanced magnetic resonance imaging. Due to the progress in radiological visualization of the inner ear, some patterns have been identified and new data obtained for Meniere's disease. The choice of the best route for contrast administration (intratympanic or intravenous) is a matter of active debate. There is no consensus on the criteria for the assessment of hydrops' grade. Future developments of the technique are associated with improvements of diagnostic procedures and protocols, use of new contrast agents and diagnostic algorithms developed with consideration of the otological problem of patients.</p></abstract><trans-abstract xml:lang="ru"><p>Болезнь Меньера характеризуется приступами головокружения, неустойчивой потерей слуха и прогрессирующей утратой аудиовестибулярных функций. Приступы болезни возникают без очевидных провоцирующих факторов и приводят к  нарушению социальной адаптации больных. Методы лучевой диагностики не включены в  диагностические критерии, сформулированные Европейским согласительным документом по диагностике и  лечению болезни Меньера (2018). Вместе с тем в последнее время опубликован ряд работ, указывающих на возможность прижизненной анатомической диагностики эндолимфатического гидропса как основного субстрата болезни при помощи магнитно-резонансной томографии с  контрастированием. Благодаря прогрессу метода лучевой визуализации внутреннего уха выявлены некоторые закономерности и  получены новые данные о  болезни Меньера. Активно обсуждается вопрос о  преимущественном способе введения контрастного препарата – интратимпанальном или внутривенном. Нет согласия и относительно критериев оценки степени выраженности гидропса. Перспективы развития методики связаны с  совершенствованием диагностической техники и  протоколов, использованием новых контрастных препаратов и  диагностических алгоритмов, разработанных с  учетом отологической проблемы пациента.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Meniere's disease</kwd><kwd>endolymphatic hydrops</kwd><kwd>magnetic resonance imaging</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>болезнь Меньера</kwd><kwd>эндолимфатический гидропс</kwd><kwd>магнитно-резонансная томография</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1.Gürkov R, Flatz W, Louza J, Strupp M, Ertl-Wagner B, Krause E. In vivo visualized endolymphatic hydrops and inner ear functions in patients with electrocochleographically confirmed Ménière's disease. Otol Neurotol. 2012;33(6):1040–1045. doi: 10.1097/MAO.0b013e31825d9a95.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>2. Wright T. 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