THE ROLE OF LABORATORY EXAMINATION IN RED EYE SYNDROME

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Abstract

Aim: To analyze etiological structure of inflammatory diseases of ocular surface. 

Materials and methods: The study included outpatients (n = 49) who referred to Ophthalmological office at the Herpetic center during the period 2012 to 2014. Complaints duration was 60.65 ± 12.28 days. All patients underwent routine ophthalmologic examination; tear and/or conjunctival scraping PCR for type 1 and 2 herpes simplex viruses, varicella-zoster virus, cytomegalovirus, Epstein-Barr virus, type 6 human herpesvirus, adenoviruses, enteroviruses, ureaplasma, chlamydia; conjunctival swab microbiology; eyelash microscopy for eyelash mites. 

Results: After the examination, all patients were divided into three groups: 1) with herpesvirus infections of the eye (n = 24), 2) with non-herpetic infection of the eye (enterovirus, adenovirus, bacteria, fungi, n = 18), 3) with ocular surface lesions due to non-infectious causes (n = 7). In three cases U. urealyticum was detected, doxycycline was administrated. Identification of pathogens in the groups 1 and 2 resulted in effective causal treatment with subsequent clinical recovery. Exclusion of infection in the third group allowed to avoid inappropriate antibacterial or antiviral therapy. 

Conclusion: In patients with chronic red eye syndrome of unknown etiology, laboratory examination of tear and/or conjunctival scraping is essential for differentiating between infectious and non-infectious disease.

About the authors

G. M. Chernakova

Herpetic Center; 21B Michurinskiy prospekt; Russian Medical Academy of Postgraduate Education; S.P. Botkin City Clinical Hospital of the Moscow Public Health Department, Branch 1

Author for correspondence.
Email: vernikov@mail.ru

MD, PhD, Ophthalmologist; Associate Professor, Ophthalmology Department; Hospital Advisor

Russian Federation

E. A. Kleshcheva

Herpetic Center; 21B Michurinskiy prospekt; Russian Medical Academy of Postgraduate Education; S.P. Botkin City Clinical Hospital of the Moscow Public Health Department, Branch 1

MD, PhD, Ophthalmologist; Assistant Professor, Ophthalmology Department

Russian Federation

A. S. Obrubov

S.P. Botkin City Clinical Hospital of the Moscow Public Health Department, Branch 1

MD, PhD, Ophthalmologist Russian Federation

A. A. Ovsyanko

Herpetic Center; 21B Michurinskiy prospekt; Russian Medical Academy of Postgraduate Education

Ophthalmologist; PhD student, Ophthalmo logy Department

Russian Federation

T. B. Semenova

Herpetic Center; 21B Michurinskiy prospekt

MD, PhD, Professor, The Member of the Russian Academy of Medical and Technical Sciences, Head Physician

Russian Federation

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Copyright (c) 2015 Chernakova G.M., Kleshcheva E.A., Obrubov A.S., Ovsyanko A.A., Semenova T.B.

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